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This book offers a unique insight into the medulloblastoma world, and provides both a broad review and detailed analysis of this brain tumour. It starts with the history of medulloblastoma as a term, and as a distinct entity in nosology, and then explores in depth, the diagnosis, genetics, neurosurgical, and oncological management of medulloblastoma patients, as well as their outcome and long-term complications. Furthermore, novel therapies and next generation clinical trials in medulloblastoma are discussed. This landmark text is written by leading authorities in the research and treatment of medulloblastoma. It provides information based on clinical trials, major clinical series, and the a...
There are not many books published about esophageal cancer. Esophageal cancer is an entity that must be treated from a multimodal approach. Recent advances in diagnosis, anesthetic aspects and perioperative care, among others, are summarized in this book. This book is written in a simple way and intends to cover the main aspects of this type of cancer. It incorporates the latest evidence about the diagnosis, management and treatment of esophageal cancer from a multimodal point of view. Epidemiologists, gastroenterologists, oncologists and surgeons have all participated in the elaboration of this book. It is divided into ten chapters, describing all esophageal cancer topics and each chapter h...
Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of Non-Hodgkin lymphomas with a variety of clinical presentation and outcomes. The diagnosis and treatment of CTCLs have evolved significantly with advances in our understanding of their pathogenesis and biological behaviors through immunophenotypic, molecular, and cytogenetic analysis and clinical correlation. The diagnosis and classification of CTCLs depend on integration of clinical presentation, histology, immunophenotype, molecular and/or cytogenetic findings. Accurate diagnosis and staging are essential for proper treatment and prognosis of the patients. The book Cutaneous T-Cell Lymphoma (CTCL): Clinical Features, Diagnosis ...
This book presents and discusses research in the study of breast cancer diagnosis and prevention. Topics discussed include strategies for the prevention of breast cancer; health benefits and breast cancer screenings; access to mammography facilities; the reduction in the risk of human breast cancer by selective cyclooxygenase-2 (COX-2) inhibitors and breast cancer perceptions and knowledge among women living in a rural community.
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Acute myeloid leukemia (AML) is an aggressive bone marrow cancer associated with high morbidity and mortality and most commonly affects older patient populations. In this book, the clinical presentation of acute myeloid leukemia are presented. Other chapters present the differences in the outcomes of two subtypes of core binding factor (CBF) acute myeloid leukemia (AML); examine the occurrence of the Philadelphia chromosome in AML with core binding factor leukemia; and therapeutic options of older patients with AML.
This book discusses the global attitudes regarding blood donations, its safety and future directions. Chapter One provides a brief overview of the ethics of blood donations. Chapter Two focuses on the epidemiological aspects of the hepatitis C virus infection among seekers of serological tests in blood banks in Pará, Brazilian Amazon. Chapter Three discusses statistical control of the production of blood components using variables and attributes charts, and capacity indexes. Chapter Four demonstrates the use of cluster analysis and item response theory for the assessment of transfusion-related knowledge of nurses. Chapter Five reviews a quantitative/qualitative approach to better understand motivations of apheresis donors in Quebec, Canada.
This book was written for the complex scenario of fertility-sparing management in gynaecological cancer. In reproductive age women, appropriate counselling is mandatory in any cancer diagnosis, including discussing the long-term consequences of the different treatment options on fertility and the possibility of fertility preservation. However, women affected by gynaecological cancer must consider that treatment options including hysterectomy and bilateral oophorectomy in most cases. Therefore, in gynaecological cancer, the standard treatment often consists of an inevitable loss of fertility. The direct consequence is that fertility preservation management does not always result in the optima...
The diagnosis and treatment of Diffuse large B-cell lymphoma (DLBCL) have evolved significantly in the past decade. With advances in our understanding of DLBCL through the application of immunophenotypic, molecular cytogenetic analysis and clinical correlation, a growing number of discrete subtypes and entities of DLBCL have been recognised, along with improved prognostic stratification and treatment strategies. A simple diagnosis of DLBCL and standard chemotherapy are no longer appropriate for every individual patient anymore. Pathologists and practicing clinicians need to be familiar with current literature in order to achieve the best treatment of their patients. This book aims to provide...