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Short case studies, based on real stories from the health care arena, ensure that each chapter of this book is rooted in descriptions of nursing practise that are grounded, salient narratives of nursing care. The reader is assisted to explore the ethical dimension of nursing practice: what it is and how it can be portrayed, discussed, and analysed within a variety of practice and theoretical contexts. One of the unique contributions of this book is to consider nursing not only in the context of the individual nurse – patient relationship but also as a social good that is of necessity limited, due to the ultimate limits on the nursing and health care resource. This book will help the reader...
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She’s young, single and about to achieve her dream of creating incredible video games. But then life throws her a one-two punch: a popular streamer gives her first game a scathing review. Even worse, she finds out that same troublesome critic is now her new neighbor! A funny, sexy, and all-too-real story about gaming, memes, and social anxiety. Come for the plot, stay for the doggo.
With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain
Nonlinear optics is one of the most important fields of science and engineering, covering the generation, transmission, and control of the whole spectrum of laser pulses in solids, liquids, gases, and fibers. In turn, one of the most important ultrafast nonlinear optical processes is the supercontinuum generation - the production of intense ultrafast broadband "white light" pulses. This book is intended to fill the need of both scientists and graduate students for a single source book containing the most necessary and relevant material on supercontinuum technology. It reviews the basic principles, surveys research results, and presents the current thinking of experts in the supercontinuum field.
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Test films, pilots, trial series, limited runs, summer tryouts--by whatever name, televison networks have produced thousands of experimental shows that never made it into the regular line-up. Some were actually shown, but failed to gain an audience; many others never even made it on the air. This work includes more than 3,000 experimental television programs, both aired and unaired, that almost became a series. Entries include length, network, air date (if appropriate), a fact-filled plot synopsis, cast, guest stars, producer, director, writer, and music coordinator. Fully indexed.