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The Pathophysiology of the Microcirculation
This book is devoted to the pathophysiology of the microcirculation, an intensely studied area of the circulatory system. Featuring contributions from 29 top investigators in the field, the book begins with an introduction to the general structure of the normal microvascular system, with special emphasis on the characteristics of blood vessel segments collectively comprising the system. Significant areas covered in the book include angiogenesis, neoplasias, hypertension, shock, ischemia/reperfusion, diabetes, immunologic injury, and thermal injury. It also covers the effects of aging and environmental factors on the microcirculation-topics not often examined in depth. More than 80 figures and tables illustrate key concepts throughout the book.
Practical Peer-to-Peer Teaching and Learning on the Social Web
On the Social Web, people share their enthusiasms and expertise on almost every topic, and based on this, learners can find resources created by individuals with varying expertise. Through this trend and the wide availability of video cameras and authoring tools, people are creating DIY resources and sharing their knowledge, skills, and abilities broadly. While these resources are increasing in availability, what has not been explored is the effectiveness of these resources, peer-to-peer teaching and learning, and how well this content prepares learners for professional roles. Practical Peer-to-Peer Teaching and Learning on the Social Web explores the efficacies of online teaching and learning with materials by peers and provides insights into what is made available for teaching and learning by the broad public. It also considers intended and unintended outcomes of open-shared learning online and discusses practical ethics in teaching and learning online. Covering topics such as learner roles and instructional design, it is ideal for teachers, instructional designers and developers, software developers, user interface designers, researchers, academicians, and students.
Xenobiotics and Inflammation
The affect of xenobiotics on host resistance in general and specific immune functions has become the focus of much current research. This book synthesises current information on how chemicals (xenobiotics) can affect the immune system to cuse dysfunction, focusing on the process of inflammation. It provides a much needed, single-source reference for researchers investigation the mechanisms responsible for altered host resistance following exposture to xenobiotics. Emphasis is placed on the roles of cytokines and growth factors in the inflammatory process and how such processes are altered and modulated by xenobiotics. This volume contains information pertinent to those exploring cell growth, angiogenesis, hematopoetic differentiation, and recruitment to and proliferation of cells in various tissue sites. This volume brings together experts in inflammation, cytokines, cell growth, immunology and toxicology to provide a highly yseful volume modulated by chemicals. Divided into three sections, the book offers an organ system approach to understanding inflammation and xenobiotics.
Water productivity, the yield gap, and nutrition
The report uses a nutritional water productivity (NWP) framework to interpret the relationship between nutrition and water in the context of water challenges. It argues that higher yields – of both staple and nutritious crops – are possible, even in water-stressed areas. This will require an agricultural transformation that ensures that efforts to enhance water productivity are linked to the promotion of healthy diets. Increasing water productivity and stabilizing yields at realistic levels will also be crucial to increasing the resilience of farmers. Better coordination and timing of water and other inputs, notably fertilizers and improved seeds, is likely to enhance productivity and...
Metal Ions in Biology and Medicine
Every two years, the world's leading specialists meet to exchange information on the most recent advances in understanding metals and the part they play in treating some diseases, especially cancer. Most of the elements in our environment are metals. Some are essential for life, such as copper, iron, magnesium, manganese, nickel and zinc; others are toxic, such as arsenic, cadmium, lead and mercury. This book aims to help advance our knowledge of the role of metal ions in a number of fields in biology and medicine. It reproduces the papers given at the International Symposium on Metal Ions in Biology and Medicine organised in Munich in May 1998.
Biological Reactive Intermediates IV
The finding that chemicals can be metabolically activated to yield reactive chemical species capable of covalently binding to cellular macromolecules and the concept that these reactions could initiate toxicological and carcinogenic events stimulated a meeting by a small group of toxicologists at the University of Turku, in Finland, in 1975 (Jollow et al. , 1977). The growing interest in this field of research led to subsequent symposia at the University of Surrey, in England in 1980 (Snyder et al. , 1982), and the University of Maryland in the U. S. A. in 1985 (Kocsis et al. , 1986). The Fourth International Symposium on Biological Reactive Intermediates was hosted by the Center for Toxicol...
A Comparative Analysis of the Technical Efficiency of Rain-fed and Smallholder Irrigation in Ethiopia
Agriculture is the most significant contributor to Ethiopia’s economy. Most of the agricultural production is under rainfed conditions and thus extremely sensitive to rainfall variability. Irrigation development, including smallholder irrigation, is used by the Ethiopian Government to attempt to mitigate the effects of rainfall variability. In this study, we look at smallholder irrigation – modern and traditional irrigation systems. A detailed description of the cropping patterns is given. The stochastic frontier production function approach is used to estimate technical inefficiency, and constraints to production are analyzed. Since the traditional system is found to be efficient but on a lower production frontier, the study shows that significant gains can be made by raising the frontier of the traditional systems and increasing the efficiency of the modern systems. Among the production constraints studied were land preparation, soil fertility, weed control, pests and diseases, soil erosion, input access and moisture deficiency. The most significant constraints on the irrigated systems were input access and moisture deficiency.
Oxidative Injury in Dermatopathology
Dermatology is a complex and puzzling world of itching bumps, pim ples, and rashes. The multitude of clinically distinct skin diseases, their frequently unresolved pathogenesis, and the exponentially in creasing amount of scientific information add to the confusion about skin diseases. The great prevalence of skin diseases makes them an urgent priority for intensive research effort, and although many scientists and academic clinicians are vigorously trying to uncover we are only at the very brink of understanding the etiol their secrets, ogy of most dermatoses. The principle mechanisms of general organ pathology (physical, chemical, microbial, ischemic, degenerative, and neoplastic disturb a...
Investing in agricultural water management to benefit smallholder farmers in Ethiopia. AgWater Solutions Project country synthesis report
The AgWater Solutions Project, carried out between 2009 and 2012, focused on resolving water issues faced by smallholder farmers. The project examined existing Agricultural Water Management (AWM) solutions, together with factors that influence their adoption and scaling up. The project aimed to identify investment opportunities in AWM that have high potential to improve the incomes and food security of poor farmers. The work was undertaken in the African countries of Burkina Faso, Ethiopia, Ghana, Tanzania and Zambia, and in the Indian States of Madhya Pradesh and West Bengal. This Working Paper series summarizes results and recommendations from the research carried out in each of these countries and states.
Cutaneous Drug Reactions
A Karger 'Publishing Highlights 1890-2015' title A wealth of information and its clear organization make this survey of cutaneous drug reactions an indispensable reference source for the dermatologist and any physician prescribing drugs. It is the only publication which offers a systematic approach to the whole therapeutic armamentarium, as well as to the signs and symptoms affecting skin, mucous membranes, nails and hair. The information, documented by 5600 references, is presented in tabular form to allow quick location of needed data. Convenient indexes permit the user to trace either the side effects of specific drugs and their frequency or the possible drug causes of cutaneous reactions. The drug index contains both generic and brand names. Now entirely in English, this expanded and updated edition is easy to use and serves as both a practical diagnostic aid and an important source of references to the world literature.
