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Neuroactive metabolites of ethanol: a behavioral and neurochemical synopsis
Ethanol is a very elusive drug, which has mechanisms of action that are diverse and relatively non-selective. Moreover, ethanol has been demonstrated to be a biologically active substance by itself, but also a pro-drug of the neuroactive metabolites, acetaldehyde and acetate. Acetaldehyde has traditionally been known as a toxic substance with several effects on multiple systems. However, in the last few decades evidence has accumulated to reveal the specific and, in some instances, distinct neural actions of acetaldehyde and acetate that are in part responsible for some of the observed psychoactive effects of ethanol. The present issue will address these challenges to provide an up-to-date s...
Ethanol, Its Active Metabolites, and Their Mechanisms of Action: Neurophysiological and Behavioral Effects
Ethanol, the main psychopharmacologically active ingredient of alcoholic drinks, represents a paradigmatic example of a research subject intrinsically able to perpetually self-generate interdisciplinary cutting-edge investigations. This eBook was inspired by the aim of providing an up-to-date characterization of the diverse effects of ethanol, of the possible mechanisms of action on different intracellular systems as well as of the hypothesized actions of ethanol and/or its metabolites on various neurotransmitters and neuromodulators. Indeed, the eBook provides a factual example of an excellent synthesis on the complex relationship between ethanol and its main biologically active metabolites...
Recent Developments in Neuroscience Research on Human Motivation
This volume provides new insight into motivation theory by integrating noteworthy neuroscience research findings on motivation. This volume is dedicated to advancing our understanding of brain mechanisms of underlying motivational phenomena, including reward, approach, autonomy, intrinsic motivation, learning, effort, curiosity, and self-control.
Adenosine
Homeostasis of key metabolites and metabolic health affects all bodily systems. Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system – including developmental disorders, acute nervous system injury, and neurodegenerative disorders. Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic functions. Increasingly it is appreciated that restoring metabolic health could promote normal nervous system activity, and improve behavior and cognition. Adenosine: A Key Link Between Metabolism and Cen...
Proof
Presents a look at the science of alcohol production and consumption, from the principles behind the fermentation, distillation, and aging of alcoholic beverages, to the psychology and neurobiology of what happens after it is consumed.
XXXII INTERNATIONAL CONFERENCE OF THE SPANISH SOCIETY FOR COMPARATIVE PSYCHOLOGY
The XXXII International Conference of the Spanish Society for Comparative Psychology has been organized by the Spanish Society of Comparative Psychology (SEPC), at the University of Almeria, on 21st, 22nd and 23rd September of 2022. The present work includes the abstracts of the different symposia, oral communications and poster sessions presented during the meetings. There were 2 plenary lectures about “Perceptual learning mechanisms and its implications for eating behavior” presented by Isabel de Brugada Sauras (University of Granada) and “Expanding the scope of associative learning models by incorporating the untidiness of natural stimuli” presented by Federico Sanabria and Cristina Santos (Arizona State University). Moreover, There were 30 symposia (divided into 7 sessions), 41 oral communications (divided into 8 sessions), and 55 posters (divided into 3 sessions). Finally, 21 people constituted the organizational committee and 27 people constituted the scientific committee.
Behavioral Neuroscience of Motivation
This volume covers the current status of research in the neurobiology of motivated behaviors in humans and other animals in healthy condition. This includes consideration of the psychological processes that drive motivated behavior and the anatomical, electrophysiological and neurochemical mechanisms which drive these processes and regulate behavioural output. The volume also includes chapters on pathological disturbances in motivation including apathy, or motivational deficit as well as addictions, the pathological misdirection of motivated behavior. As with the chapters on healthy motivational processes, the chapters on disease provide a comprehensive up to date review of the neurobiological abnormalities that underlie motivation, as determined by studies of patient populations as well as animal models of disease. The book closes with a section on recent developments in treatments for motivational disorders.
The Adenosinergic System
Adenosine A2A receptor antagonists have shown great promise in the treatment of Parkinson's Disease and alleviation of symptoms. This book addresses various aspects of this class of drugs from their chemical development to their clinical use. Among the many insightful chapters contained in this book, there are three unique reviews that have not previously been published in any format: (1) a history of istradefylline, the first A2A antagonist approved for treatment of Parkinson's Disease, (2) an overview of neuroimaging studies in human death and disease and (3) a study of urate as a possible biomarker and neuroprotectant.
The Psychological Construction of Emotion
This volume presents cutting-edge theory and research on emotions as constructed events rather than fixed, essential entities. It provides a thorough introduction to the assumptions, hypotheses, and scientific methods that embody psychological constructionist approaches. Leading scholars examine the neurobiological, cognitive/perceptual, and social processes that give rise to the experiences Western cultures call sadness, anger, fear, and so on. The book explores such compelling questions as how the brain creates emotional experiences, whether the "ingredients" of emotions also give rise to other mental states, and how to define what is or is not an emotion. Introductory and concluding chapters by the editors identify key themes and controversies and compare psychological construction to other theories of emotion.
Neuroeconomics
The brain is the organ of decision making, and evolved to maximize the outcomes desirable for the survival and reproduction of the species. Compared to the sensory and motor functions of the brain, however, the process of decision making is less accessible to direct experimental manipulations and hence requires more careful theoretical analyses. Indeed, the principle of optimality and frequent departures of human behaviors from those predicted for optimal rational decision makers have long been studied experimentally as well as theoretically. However, it is only recently that neurobiological studies of decision making started exploiting the framework previously developed in economics and psy...
