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Genetics and Epigenetics of Psychiatric Diseases, 2nd Edition
Psychiatric diseases have a highly complex etiology, aggregating in families but not segregating in a traditional Mendelian manner. Recent approaches to understanding the causes of psychiatric disease have focused on describing the genetic contribution to major psychiatric illnesses; the use of large-scale genome-wide association studies (GWAS) and exome sequencing has enabled a systematic exploration of genetic risk factors and identified over 100 independent genomic loci significantly associated with psychiatric diseases; however, there remains uncertainty about the causal genes involved in disease pathogenesis, and how their function is regulated. Since many GWAS variants reside in non-co...
Handbook of Engineering and Specialty Thermoplastics, Volume 3
The book summarizes many of the recent technical research accomplishments in the area of engineering polymers, such as oxygen containing main chain polymers (Polyether and Polyesters). The book emphasizes the various aspects of preparation, structure, processing, morphology, properties and applications of engineering polymers. Recent advances in the development and characterization of multi component polymer blends and composites (maco, micro and nano) based on engineering polymers are discussed in detail. The content of the book is unique as there are no books which deal with the recent advances synthesis, morphology, structure, properties and applications of engineering polymers and their blends and composites including nanocomposites. It covers an up-to-date record on the major findings and observations in the field.
Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents
This book is a comprehensive resource on psychotropic medications, detailing the latest methods for defining their characteristics, their use in different patient populations, and drug-drug interactions; an important collection of information forclinicians, students, researchers, and members of the pharmaceutical industry alike. The first section provides the foundational principles of these drugs. Mathematical modeling of parameters that affect their entryto,and exit from, the central nervous system (CNS) compartment are presented on an individual basis and then applied to target populations with specific disease states. Methods and characteristics that inform the transfer of these drugs fr...
Disaster Emergency Management
Survival in times of disaster is a question of utmost importance to both the victims of those events and to the professionals and people in authority who are there to serve them. In Disaster Emergency Management, Liza Ireni Saban examines what leads some nations, communities, and individuals to rise to the occasion during these times of trauma, while others do not. Utilizing case studies of China, Indonesia, Japan, and the United States, she focuses in particular on the dilemma faced by local emergency officials who, rather than elected officials, find themselves "on the front lines," suddenly confronted with complex public problems. Recent studies have pointed to a breakdown of government and bureaucratic decision making in the face of intense crisis situations. Saban demonstrates the inadequacies of grappling with what are in truth contested ethical issues within a framework whose approach is technical-rational. She draws on communitarian ethics to redefine the role of the bureaucrat so that community resilience, through attention to local values and needs, is fostered prior to the actual crisis.
Epstein-Barr Virus and Associated Diseases
Text in English & French. This book gathers together all the most recent world-wide knowledge in the various fields of research into the Epstein-Barr virus (EBV), from the most fundamental subjects (virology, molecular and cellular biology and immunology) through epidemiology, pathological anatomy, clinical research and therapeutics. Featured in the book are highly original chapters dealing with malignant lymphomas in AIDS patients, detection and prevention in developing countries, formulation of an anti-EBV vaccine. This comprehensive and clearly written book is a valuable and essential tool for all researchers and clinicians.
