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Genetics and Epigenetics of Psychiatric Diseases, 2nd Edition
Psychiatric diseases have a highly complex etiology, aggregating in families but not segregating in a traditional Mendelian manner. Recent approaches to understanding the causes of psychiatric disease have focused on describing the genetic contribution to major psychiatric illnesses; the use of large-scale genome-wide association studies (GWAS) and exome sequencing has enabled a systematic exploration of genetic risk factors and identified over 100 independent genomic loci significantly associated with psychiatric diseases; however, there remains uncertainty about the causal genes involved in disease pathogenesis, and how their function is regulated. Since many GWAS variants reside in non-co...
New Directions in Bioprocess Modeling and Control
Models offer benefits even before they are put on line. Based on years of experience, the authors reveal in New Directions in Bioprocess Modeling and Control that significant improvements can result from the process knowledge and insight that are gained when building experimental and first-principle models for process monitoring and control. Doing modeling in the process development and early commercialization phases is advantageous because it increases process efficiency and provides ongoing opportunities for improving process control. This technology is important for maximizing benefits from analyzers and control tool investments. If you are a process design, quality control, information s...
People, Citizen, and User
The book examines the changing discourses of Chinese audience research in the past four decades, aiming to shed light on the complicated relationships among China’s media, audiences, and society. With the new sociology of knowledge, it adopts Laclau and Mouffe’s discourse theory as a meta-theoretical framework and interprets the concept of audience as a floating signifier. Based on the corpus of Chinese academic journal papers, the author divides the scope of analysis into four phases. In each period, Chinese audience research was related closely to the changing societal and academic contexts and hegemonic struggle as a whole. In addition, it discusses the relation between ‘western’ audience theories and Chinese audience research, as well as the contingency and rigidity of discourses in Chinese audience research. The book contributes to the understanding of Chinese communication research in the changing societal context and will be valuable for scholars of media and communication studies or China studies.
