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This book provides a comprehensive, state-of-the art review of hematopoietic stem cell transplantation (HSCT) for sickle cell disease (SCD). The book reviews new data about risk prediction for severe SCD, outlines the unique challenges of HSCT for patients with SCD, profiles the supportive care guidelines for patients who are undergoing HSCT, highlights our current understanding of the best transfusion support for SCD patients prior to, during and after HSCT, and provides new perspectives about the ethics of HSCT for pediatric patients with SCD. Published in the last few years, several landmark phase III trials that utilize matched unrelated and haploidentical donors for HSCT in SCD patients are also placed in context with respect to current management. Written by experts in the field, Sickle Cell Disease and Hematopoietic Stem Cell Transplantation is a valuable resource for physicians and researchers dealing with and interested in this challenging, yet exciting, curative therapy for sickle cell disease, that will help guide patient management and stimulate investigative efforts.
Whichever direction you travel in the Americas; north, south, east or west, this volume offers an extensive array of cool hotel options. When you're seeking just the right combination of sophisticated watering hole, deluxe private space, and cutting-edge design, these locales are for you. This guide is packed full of both alluring images and useful information. Browsing the pages, you'll get an in-depth glimpse of the carefully curated furnishings, artwork, and fine design details which make each hotel a byword for chic sophistication. Along with fine service and precise attention to detail, they all offer the ambiance and amenities sure to please even the choosiest of hip travelers. English/German/French edition.