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Pediatric Neurogastroenterology
Neurogastroenterology is devoted to "study the interface of all aspects of the digestive system with the different branches of the nervous system". Over the past 15 years advances in this field has greatly improved our understanding in primary functional and motility disorders in children. Neurogastroenterology has also begun to revolutionize our vision of "organic" diseases like inflammatory bowel disease, obesity, diabetes as well as microbial-host interactions. Major advances have also been achieved during these years in the knowledge of mechanisms of development of the enteric nervous system at the molecular level allowing a better understanding of diseases related to developmental anoma...
Curbside Consultation in Pediatric GI
Are you looking for concise, practical answers to those questions that are often left unanswered by traditional pediatric GI references? Are you seeking brief, evidence-based advice for complicated cases or controversial decisions? Curbside Consultation in Pediatric GI: 49 Clinical Questions provides quick answers to the tricky questions most commonly posed during a “curbside consultation” between pediatricians. Drs. Joel R. Rosh and Athos Bousvaros have designed this unique reference which offers expert advice, preferences, and opinions on tough clinical questions commonly associated with pediatric GI. The unique Q&A format provides quick access to current information related to pediatr...
Pathophysiology of Gastrointestinal Acute Graft-versus-host Disease and the Potential Role of Glucagon-like Peptide 2
Abstract: Acute graft-versus-host disease (aGVHD) is a life-threatening complication after allogeneic haematopoietic cell transplantation, with gastrointestinal (GI) tract involvement (GI aGVHD) being one of the leading causes of morbidity and mortality. Whilst systemic steroids are the standard first-line treatment for aGVHD, approximately 50% of patients become steroid refractory (SR), which is associated with poor outcomes. Existing options for SR-GVHD are limited, and there is a significant unmet need for new non-immunosuppressive treatment approaches in patients with GI aGVHD. Here, we review newer concepts in the pathogenesis of GI aGVHD and present the evidence for the role of glucagon-like peptide 2 (GLP-2) in maintaining and protecting GI epithelial cells, including the enterocytes, intestinal stem cells and Paneth cells, which are direct targets of aGVHD. Finally, we discuss the therapeutic rationale for GLP-2 treatment as a tissue regeneration approach and the potential use of the novel GLP-2 analogue apraglutide as an adjunctive treatment for GI aGVHD
Current Pediatric Therapy
Generations of practitioners have turned to this reference for the most recent advances in therapeutic care, including medical and surgical therapies, preventive medicine, adolescent gynecology, and behavioral issues. This 18th edition includes access to a Web site for convenient consultation wherever and whenever it is needed.
Conquering Your Child's Chronic Pain
“An important, compassionate book.” — Deepak Chopra “Parents! If you hava child in pain, read this book. There is hope.” — James Campbell, M.D., Professor of Jeurological Surgery and Director, Johns Hopkins University School of Medicine; Founder and President, American Pain Foundation “An outstanding book for parents of children and adolescents with chronic pain. I recommend it highly.” — Charles Berde, M.D., Ph.D., Chief, Division of Pain Medicine, Department of Anesthesiology, Children's Hospital, Boston; Professor of Anaesthesia and Pediatrics, Harvard Medical School “A valuable and important book that will be appreciated by every family struggling with a child in pain...
Bioactive Foods in Promoting Health
Feature: Heavy emphasis on clinical applications (benefits and/or lack thereof) as well as future biomedical therapeutic uses identified in animal model studies Benefits: Focused on therapies and data supporting them for application in clinical medicine as complementary and alternative medicines Feature: Key insights into gut flora and the potential health benefits thereof. Benefit: Health scientists and nutritionists will use this information to map out key areas of research. Food scientists will use it in product development. Feature:Information on pre-and probiotics as important sources of micro-and macronutrients Benefit: Aids in the development of methods of bio-modification of dietary plant molecules for health promotion.-
Pediatric Annals
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Gastrointestinal Emergencies, An Issue of Emergency Medicine Clinics
This issue of Emergency Medicine Clinics, guest edited by Drs. Angela Mills and Anthony Dean, will include articles on the following topics: Approach to acute abdominal pain;Evaluation of abdominal pain in older adults; Evaluation of abdominal pain in the pediatric population; Imaging and laboratory testing in acute abdominal pain;Esophageal and gastric emergencies; and Anorectal emergencies and foreign bodies in the gastrointestinal tract.
Generation in Waiting
Young people in the Middle East (15–29 years old) constitute about one-third of the region's population. Growth rates for this age group trail only sub-Saharan Africa. This presents the region with an historic opportunity to build a lasting foundation for prosperity by harnessing the full potential of its young population. Yet young people in the Middle East face severe economic and social exclusion due to substandard education, high unemployment, and poverty. Thus the inclusion of youth is the most critical development challenge facing the Middle East today. A Generation in Waiting portrays the plight of young people, urging greater investment designed to improve the lives of this critica...
