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The Revolution's Child
Set against the turbulent backdrop of the Russian revolution and two World Wars, The Revolution's Child is a sweeping tale of passion, love, loss, exile, and reunion featuring an unforgettable cast of characters.
Cancer Vaccines
This volume focuses on the laboratory and clinical experience with targeting viral onco-antigens, while also reviewing the approaches to targeting self-cancer antigens in cancers of non-viral origin, where self-tolerance has been a challenge. It emphasizes the importance of selecting the right vaccine platform to induce a successful immune response against cancer antigens. In addition, the volume discusses the advances made with genetic vaccines, including recent advances with DNA vaccines and the rapid transition of mRNA vaccines from the laboratory to bedside. The new avenues opening up for cancer immunotherapy underline the importance of combinational approaches using cancer vaccines with costimulatory antibodies, which may dramatically improve cancer treatment. This book is intended for all translational researchers and clinicians who aspire to develop novel vaccination approaches for cancer patients with unmet clinical needs.
Uncertainty in Global Politics
This book engages in a constructive, practical debate on the nature and effects of uncertainty in global politics. International contributors explore the processes associated with different forms of uncertainty in the context of environmental issues, diplomacy and international negotiations, and conflict and security. From the collapse of the Soviet Union to the 1997 and 2008 financial crises to the Arab Uprisings and the European migrant crisis and the COVID-19 pandemic, assessments of many events with lasting consequences on the global order have begun with: “why didn’t we see this coming?” There is much to learn from how phenomena that affect the global order generate uncertainty an...
Cancer Immunotherapy
There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumor immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational...
Advances in Head and Neck Cancer Immunology and Immunotherapy
Understanding the immunology of different cancers has led to great advances in developing cancer immunotherapies which are successfully used in generating effective anti-tumour immune responses. Head and neck cancers are no exception and various immunotherapies are now under study for the treatment of this diverse group of diseases. The articles in in this eBook provide a range of topics that highlight some of the latest advances in head and neck cancer immunology and immunotherapy. The authors of these articles provide their unique insight and expertise and suggest future directions for translational clinical research.
Varieties of Russian Activism
Despite decades under Putin's rule, it is too simplistic to assert that authoritarianism in Russia has eliminated activism, especially in relation to everyday life. Instead, we must build an awareness of diverse efforts to mobilize citizens to better understand how activism is shaped by and, in turn, shapes the regime. Varieties of Russian Activism focuses on a broad range of collective actions addressing issues from labor organizing to housing renovation, religion, electoral politics, minority language rights, and urban planning. Contributors draw attention to significant forms of grassroots politics that have not received sufficient attention in scholarship or that deserve fresh examination. The volume shows that Russians find novel ways to redress everyday problems and demand new services. Together, these essays interrogate what kinds of practices can be defined as activism in a fast-changing, politically volatile society. An engaging collection, Varieties of Russian Activism unites leading scholars in the common aim of approaching the embeddedness of civic activism in the conditions of everyday life, connectedness, and rising society-state expectations.
Globalisation and National Identity in History Textbooks
Globalisation and National Identity in History Textbooks: The Russian Federation, the 16th book in the 24-volume book series Globalisation, Comparative Education and Policy Research, discusses trends in dominant discourses of identity politics, and nation-building in school history textbooks in the Russian Federation (RF). The book addresses one of the most profound examples of the re-writing of history following a geo-political change. Various book chapters examine debates pertaining to national identity, patriotism, and the nation-building process. The book discusses the way in which a new sense of patriotism and nationalism is documented in prescribed Russian history textbooks, and in the...
AACR 2019 Proceedings: Abstracts 1-2748
American Association for Cancer Research 2019 Proceedings: Abstracts 1-2748 - Part A
