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Protein Post-Translational Modifications in the Nervous System: from Development to Disease and Ageing
Post-translational modifications (PTMs) increase the functional diversity of the proteome by reversibly or irreversibly modifying proteins during or after their synthesis. Thereby, they contribute to the structural and functional variety of proteins, conveying a complexity to the proteome that is significantly higher than the coding capacity of the genome. Moreover, providing another level of epigenetic regulation, PTMs of histone proteins in particular contribute to the modulation of gene accessibility and specific cell expression profiles. PTMs include enzymatically controlled modifications such as phosphorylation, glycosylation, acetylation, methylation, ubiquitination, or proteolysis as ...
Migration from the Russian Empire: January 1888-May 1889
Compilation of data on passengers of Russian nationality who immigrated to the United States from Russian territories between 1875 and 1891. Passenger lists are arranged chronolgically by date of arrival at New York harbor.
Developments and Applications of Calcium Phosphate Bone Cements
This book presents a state-of-the-art review of the latest advances in developing calcium- phosphate bone cements and their applications. It covers the synthesis methods, characterization approaches, material modification and novel binders, as well as the fabrication technologies of calcium-phosphate-based biomaterials in regenerative medicine and their clinical applications. It also highlights methodologies for fabricating scaffolds, biofunctional surfaces/interfaces and subsequently modulating the host response to implantable/injectable materials, and integrates a series of discussions and insights into calcium-phosphate cements and constructs in bone regenerative medicine. As such, the book not only covers the fundamentals but also opens new avenues for meeting future challenges in research and clinical applications.
The Routledge Companion to Literary Urban Studies
Over the past decades, the growing interest in the study of literature of the city has led to the development of literary urban studies as a discipline in its own right. The Routledge Companion to Literary Urban Studies provides a methodical overview of the fundamentals of this developing discipline and a detailed outline of new directions in the field. It consists of 33 newly commissioned chapters that provide an outline of contemporary literary urban studies. The Companion covers all of the main theoretical approaches as well as key literary genres, with case studies covering a range of different geographical, cultural, and historical settings. The final chapters provide a window into new ...
The Adelphean
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Supported Catalysts and Their Applications
The need to improve both the efficiency and environmental acceptability of industrial processes is driving the development of heterogeneous catalysts across the chemical industry, including commodity, specialty and fine chemicals and in pharmaceuticals and agrochemicals. Drawing on international research, Supported Catalysts and their Applications discusses aspects of the design, synthesis and application of solid supported reagents and catalysts, including supported reagents for multi-step organic synthesis; selectivity in oxidation catalysis; mesoporous molecular sieve catalysts; and the use of Zeolite Beta in organic reactions. In addition, the two discrete areas of heterogeneous catalysis (inorganic oxide materials and polymer-based catalysts) that were developing in parallel are now shown to be converging, which will be of great benefit to the whole field. Providing a snapshot of the state-of-the-art in this fast-moving field, this book will be welcomed by industrialists and researchers, particularly in the agrochemicals and pharmaceuticals industries.
I'll Take You There
Behind every good man is a great woman - or three A New York Times bestseller: the kaleidoscopic new novel from Wally Lamb, author of She's Come Undone. Every Monday, sixty-year-old Felix Funicello sets up a new film for his weekly club at an old-fashioned cinema. But one night, he is confronted by an unanticipated guest: the ghost of Lois Weber. Once a trailblazing director from the silent film era, Lois invites Felix to watch a new feature on the big screen – scenes from his past. As these magical movies play before him, Felix begins to understand how a trio of unforgettable women have shaped his history. An evocative and kaleidoscopic convergence of Hollywood, feminism and family secrets, I’ll Take You There is a radiant homage to a single life and to the resiliency, strength and power of women.
Diari e taccuini
Considerata per tutta la vita la regina del mystery, Patricia Highsmith è oggi riconosciuta come “una delle più grandi scrittrici moderniste” (Gore Vidal). Amata dai lettori di tutto il mondo, la Highsmith non ha mai autorizzato una propria biografia, lasciando fino alla fine i lettori, dal suo ritiro in Svizzera, all’oscuro delle vere ragioni dei turbamenti che si intravedono nella sua scrittura. Soltanto nel 1995, mesi dopo la sua scomparsa, l’editor Anna von Planta ha ritrovato in un cassetto i diari e taccuini dell’autrice: un patrimonio di oltre ottomila pagine manoscritte, che aiutano a scoprire il mondo segreto nascosto dietro alle sue pagine leggendarie. A partire dagli a...
