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Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.
Laparoscopy in combination with laparoscopic ultrasonography is a new staging procedure for tumors of the abdomen. The treatment of several other tumor entities, such as pancreatic and gastric cancer, lymphoma, ovarian cancer, liver malignancies, is also improved by more accurate staging. Laparoscopic staging helps prevent unnecessary laparotomies, provides much less trauma to the patient, maximum information on tumor spread, and enables palliative procedures to be performed during the staging procedure. This book provides detailed guidelines on the aim and technique of laparoscopic staging and discusses the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.
The issue of Cancers Journal entitled “Role of Medical Imaging in Cancers” presents a detailed summary of evidences about molecular imaging, including the role of computed tomography (CT), magnetic resonance imaging (MRI), single photon emission tomography (SPET) and positron emission tomography (PET) or PET/CT or PET/MR imaging in many type of tumors (i.e. sarcoma, prostate, breast and others), motivating the role of these imaging modalities in different setting of disease and showing the recent developments, in terms of radiopharmaceuticals, software and artificial intelligence in this field. The collection of articles is very useful for many specialists, because it has been conceived for a multidisciplinary point of view, in order to drive to a personalized medicine.
Recent decades have seen remarkable advances in the treatment of upper gastrointestinal malignancies, i.e., adenocarcinoma and squamous cell carcinoma as well as gastrointestinal stromal and other rare tumors of the esophagus and stomach. While, historically, surgical resection has been the sole treatment for these tumors, multimodal therapies have meanwhile proven their efficacy. At present, pre- and postoperative chemotherapy and radiotherapy, targeted drug therapy, and stage-specific surgical approaches are all indispensable cornerstones of an individualized treatment for upper gastrointestinal malignancies. With such multimodal treatment, better outcomes comprising improved quality of li...
When one deals with cancer, the hepatobiliary malignancies present a chal lenge to the oncologists that can be characterized as a series of unsolved clinical and biological dilemmas. Liver metastases from colorectal and other gastrointestinal malignancies, hepatocellular carcinoma, cholangiocar cinoma, and gall bladder cancer present an array of problems but have two features in common. These are high morbidity and mortality with an overall poor result from treatment. Why is it that hepatobiliary cancer carries with it such a dismal prognosis? First of all, these diseases present, for the most part, in an advanced state. To this point in time the oncologist has had no help from early diagnos...
This book, an international collaborative effort in the area of molecular respiratory research, showcases a broad range of multidisciplinary approaches to unravel and analyze the underlying mechanisms of a spectrum of respiratory ailments. It discusses immunological and genetic respiratory disorders, cancer, respiratory allergies and cough, sleep disordered breathing and many others. Exciting new results and up-to-date critical overviews of widely debated topics pertaining to respiratory disorders are presented. The contributions provide evidence for the growing interest of the international community of researchers in the field of respiration. The book incorporates modern molecular approaches to diagnostic and treatment solutions, underscoring the need for rational, evidence-based treatment methods. Combining cutting edge basic and clinical research with expert knowledge and experience this book is essential reading for medical students, research scientists and practicing specialists in pulmonology, immunology and allergology.
July 2022 is Sarcoma Cancer Awareness Month and at Frontiers in Endocrinology we want to highlight the recent discoveries in the field and raise awareness of the importance of early diagnosis of these cancers. Sarcomas is the general term for rare kinds of cancer growing in the bone and connective tissues. These tumors can be divided into two main groups, soft tissue sarcomas, and bone sarcomas. Interestingly, a new kind of sarcoma has been recently described, called pseudoendocrine sarcoma. The most common tissues affected by this kinds of sarcoma are bones, muscles, tendons, cartilage, nerves, fat, and blood vessels of your arms and legs, as well as many endocrine organs. It affects mainly...
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Ziel dieses Buchs ist es, die besonderen Belange alter Patienten mit Krebserkrankungen bei der Diagnosestellung, Versorgung und Therapie zusammenzufassen. Für Situationen, in denen ein standardisiertes onkologisches Vorgehen nicht angemessen scheint, erhalten behandelnde Ärzte einen fundierten Überblick über das aktuell verfügbare Wissen, um sicher den Mittelweg zwischen Über- und Unterdiagnostik sowie Über- und Untertherapie zu finden.Die Herausgeber und Autoren legen mit diesem Werk einen praktischen und umfassenden Handlungsleitfaden vor, der keine Frage offen lässt. Angesprochen sind Onkologen, niedergelassene Spezialisten, in Rehabilitationseinrichtungen Tätige sowie Hausärzte und Geriater.