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Transition Metals in Microbial Metabolism
Comprises 17 papers exploring the role of transition metals in a variety of metabolic processes, from simple interactions where the protein matrix does little more than bind an inorganic ion, to systems in which the binding site of the protein modifies the metals properties considerably, to the very complex multimetallic systems which may function as part of a supramolecular assembly. Intended as a reference for students and industry professionals, especially those working in biotechnology. Annotation copyrighted by Book News, Inc., Portland, OR
Metal Ions in Biological Systems
This volume is devoted to the research area regarding the biological properties of metal alkyl derivatives, offering an authoritative account of this subject by 16 scientists. In 11 chapters, Biological Properties of Metal Alkyl Derivatives highlights, in detail, derivatives of germanium, tin, lead, arsenic, antimony, selenium, tellurium, cobalt (vitamin B12 derivatives) and nickel (coenzyme F430), including the role of (mainly) micro-organisms in their formation. The derivatives of indium, thallium, bismuth, various transition metals and mercury are also covered to some extent, as are those of the non-metals silicon, phosphorus and sulfur, and the haloperoxidase route of the biogenesis of halomethanes by fungi and plants. The properties of these alkyl derivatives, their biosynthesis, including mechanistic aspects, their appearance in waters (rivers, lakes, oceans) and sediments, and their physiological and toxic effects are summarized.
Interplay between Metal Ions and Nucleic Acids
Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base pairs to peptide nucleic acids (PNAs) being thus of relevance, e.g., for chemistry and nanotechnology but also for molecular biology and (genetic) diagnostics.
Metal Ions in Biological Systems
Volume 32 covers metal ion bonding to phosphate, sugar and nucleobase residues; the ambidentate as well as the stacking properties of nucleotides; kinetic aspects as well as properties of nucleobase and nucleotide analogs; and the oligonucleotides and nucleic acids. It examines electron transfer reactions over a large number of base repairs in DNA, the role of metal ions in ribozymes, ternary metal-nucleic acid base-protein complexes, metal responsive gene regulation, and the structure-activity relationships of anticancer drugs and their action on DNA, including cisplatin and the role of proteins.
Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic
Volume 19, entitled Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic of the series Metal Ions in Life Sciences centers on the role of metal ions in clinical medicine. Metal ions are tightly regulated in human health: while essential to life, they can be toxic as well. Following an introductory chapter briefly discussing several important metal-related drugs and diseases and a chapter about drug development, the focus is fi rst on iron: its essentiality for pathogens and humans as well as its toxicity. Chelation therapy is addressed in the context of thalassemia, its relationship to neurodegenerative diseases and also the risks connected with iron adminis...
Plant Abiotic Stresses Physiological Mechanisms Tools and Regulation
Plant Physiologists have to certainly sort out the insufluciency of consequential researches, genuinely required for getting higher productivity, opulence and sustainability of agriculture through outstandingly promising technologies to help improvement in metabolic boundaries necessitates mainly for abiotic stress factors. The aspiration is to make stronger the vital outcome of conscientious research coupled principally with thorough perceptions of underlying mechanisms of plant tolerance under changing environments. Nevertheless, appropriate strategies by relevant ideas of paramount importance could ensure food production under extremes of stressful conditions geographically varying from o...
Advances in Plant Physiology Vol. 18
The reinforcement of Volume 18 of the Advances in Plant Physiology Series has been entirely due to commendable contributions by Scientists of Eminence in explicit fields. The enterprise of publishing the International Treatise Series on Plant Physiology has to genuinely sort out the scantiness of consequential researches, which are sincerely required for rising productivity, prosperity and sustainability of agriculture through prominently emerging technologies for reformation in metabolic boundaries necessitates mainly for abiotic stress factors. Unquestionably, our thought is to be familiar with ground-breaking science of value across the broad punitive range of the treatise. The aspiration...
The Origin and Nature of Life on Earth
Uniting the foundations of physics and biology, this groundbreaking multidisciplinary and integrative book explores life as a planetary process.
Microbial Sulfur Metabolism
This revealing book details recent developments in the study of the relationship between sulfur and the microbial agents that affect its metabolism. In recent years, new methods have been applied to study the biochemistry and molecular biology of reactions of the global sulfur cycle, the microorganisms involved and their physiology, metabolism and ecology. These activities have uncovered fascinating new insights for the understanding of aerobic and anaerobic sulfur metabolism.
