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AIDS Pathogenesis
Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS). The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.
The Central Nervous System in AIDS
Compact and clearly arranged, this book details present knowledge of AIDS research in the fields of neurology and ophthalmology. The experience gained by clinical experts through working with a large number of patients is presented together with the detailed morphologic results of neuropathology. To describe the various disease complexes, morphology takes into account all methods of result representation, including immunohistochemistry and electron microscopy. The four disciplines mentioned in the subtitle describe all aspects of the CNS with regard to AIDS, including clinically significant opthalmologic results. Richly illustrated clinical and morphological descriptions helps you to understand the widely diverse CNS symptoms as well as ophthalmic involvement.
Post Viral Fatigue Syndrome
Post-Viral Fatigue Syndrome (Myalgic Encephalomyelitis) Edited by Rachel Jenkins, Honorary Senior Lecturer, Institute of Psychiatry, London, UK and James Mowbray, Professor of Immunopathology, St Mary’s Hospital Medical School, London, UK The increasing number of reported cases of post-viral fatigue syndrome (also known as myalgic encephalomyelitis—ME—or chronic fatigue syndrome) has stimulated a major research effort into the cause and management of this condition. The progress of the research is charted in this comprehensive review of recent viral, biochemical, immunological and psychological findings. The presentation, investigation, diagnosis and treatment of post-viral fatigue syn...
BMJ
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The Neurology of HIV Infection
The Neurology of HIV Infection covers all aspects of nervous system involvement and pathology in HIV-infected individuals. Specialists in this field cover epidemiology, global aspects, pathology and pathogenesis of nervous system disease in HIV-infection. All complications, including the pathology caused by HIV itself and all opportunistic infections of the nervous system are reviewed in detail. Both central nervous and peripheral nervous system complications, including neuropathies and myopathies, are discussed. Key chapters on global developments, HIV-associated neurocognitive disorders, IRIS, stroke and neuro-aids in children complete this volume. - Covers all aspects of nervous system involvement and pathology in HIV-infected individuals - Includes the pathology caused by HIV and all opportunistic infections of the nervous system - Presents key chapters that focus on global developments, HIV-associated neurocognitive disorders, IRIS, stroke and neuro-aids in children
HIV/AIDS and Aging
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