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Product Life-Cycle Management
This book gives a comprehensive view of the most recent major international research in the field of tolerancing, and is an excellent resource for anyone interested in Computer Aided Tolerating. It is organized into 4 parts. Part 1 focuses on the more general problems of tolerance analysis and synthesis, for tolerancing in mechanical design and manufacturing processes. Part 2 specifically highlights the simulation of assembly with defects, and the influence of tolerances on the quality of the assembly. Part 3 deals with measurement aspects, and quality control throughout the life cycle. Different measurement technologies and methods for estimating uncertainty are considered. In Part 4, different aspects of tolerancing and their interactions are explored, from the definition of functional requirement to measurement processes in a PLM approach.
High-Dimensional Single Cell Analysis
This volume highlights the most interesting biomedical and clinical applications of high-dimensional flow and mass cytometry. It reviews current practical approaches used to perform high-dimensional experiments and addresses key bioinformatic techniques for the analysis of data sets involving dozens of parameters in millions of single cells. Topics include single cell cancer biology; studies of the human immunome; exploration of immunological cell types such as CD8+ T cells; decipherment of signaling processes of cancer; mass-tag cellular barcoding; analysis of protein interactions by proximity ligation assays; Cytobank, a platform for the analysis of cytometry data; computational analysis of high-dimensional flow cytometric data; computational deconvolution approaches for the description of intracellular signaling dynamics and hyperspectral cytometry. All 10 chapters of this book have been written by respected experts in their fields. It is an invaluable reference book for both basic and clinical researchers.
Supercomputing
This book constitutes the refereed proceedings of the 8th Russian Supercomputing Days on Supercomputing, RuSCDays 2022, which took place in Moscow, Russia, in September 2022. The 49 full papers and 1 short paper presented in this volume were carefully reviewed and selected from 94 submissions. The papers are organized in the following topical sections: Supercomputer Simulation; HPC, BigData, AI: Architectures, Technologies, Tools; Distributed and Cloud Computing.
Computer-aided Technologies
The aim of this book is to present the latest applications, trends, and developments of computer-aided technologies (CAx). Computer-aided technologies are the core of product lifecycle management (PLM) and human lifecycle management (HUM). This book has seven chapters, organized in two sections: "Computer-Aided Technologies in Engineering" and "Computer-Aided Technologies in Medicine." The first section treats the different aspects of PLM, including design, simulations and analysis, manufacturing, production planning, and quality assurance. In the second part of the book are presented CAx applications in medicine focused on clinical decision, diagnosis, and biosensor design. CAx plays a key role in a variety of engineering and medical applications, bringing a lot of benefits in product life cycle, extending and improving human life.
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