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Gastrointestinal and Colorectal Anesthesia
This resource stands as the only authoritative text to specifically focus on developments and best practices in anesthesiology for procedures affecting the gastrointestinal tract and related appendages. This book provides in-depth coverage of topics such as risk assessment, stress response, and scoring, as well as spans anesthetic trends and practi
Protein Kinase Technologies
Divided into two convenient sections, Protein Kinase Technologies collects contributions from experts in the field examining recent methodologies and techniques generally applicable to protein kinase research as well as to individual protein kinases which require special attention in neuroscience. These chapters will not only be practical instructions useful for readers' daily work in setting up and performing research but also thought-provoking and enjoyable reviews of recent advancements of individual protein kinases in neuroscience. Written for the highly successful Neuromethods series, this work contains the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and accessible, Protein Kinase Technologies seeks to foster cross-talk among investigators who study different protein kinases, and will also be beneficial for the entry of new investigators into this pivotal field.
The History of the Qurʾān
This first complete translation of Theodor Nöldeke’s The History of the Qurʾān offers a foundational work of modern Qurʾānic studies to the English-speaking public. Nöldeke’s original publication, as revised and expanded over nearly three quarters of a century by his scholarly successors, Friedrich Schwally, Gotthelf Bergsträsser and Otto Pretzl, remains an indispensable resource for any scholarly work on the text of the Qurʾān. Nöldeke’s segmentation of the surahs into three Meccan periods and a Medinan one has shaped all subsequent discussions of the chronology of the Qurʾān. The revisions and expansions of Nöldeke’s initial discussions of the orthography and variant readings of the text have found a new audience among those contemporary scholars who seek to create a more sophisticated understanding of the Qurʾān’s textual development.
Thermoradiotherapy and Thermochemotherapy
Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy, of ionising radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Problems remain with regard to maximizing the effects of hyperthermia as in fluenced by blood flow, heat loss, etc. The present volume defines the current knowledge relative to hyperthermia with radiation therapy and/or chemotherapy, giving a comprehensive overview of its use in cancer management. Philad...
Thymus Gland Pathology
The thymus is a gland that over the last two centuries has generated great awareness not only from the anatomical perspective but also for the physiological and pat- logical roles it plays in many disease processes. Prior to the early studies on its th anatomy and physiology in the 18 century, the thymus was believed to perform - usual and curious functions such as purification of the nervous system, providing a protective cushion for the vasculature of the superior mediastinum, fetal nouri- ment, or more spiritual roles such as being the seat of the soul, among others. D- th ing the 19 century important anatomical/physiological studies took place focusing on the role of the thymus in pathol...
Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy
This book reviews the latest developments in the design, synthesis, and molecular mechanism of action of Histone Deacetylase (HDAC) inhibitors in the context of potential cancer therapy. HDAC inhibitors are emerging as promising anticancer drug molecules that promote growth arrest, differentiation and apoptosis of cancer cells with tumor selective toxicity. The book begins with an overview of various epigenetic modifying enzymes that are involved in cancer transition and progression; before exploring the potential of HDACs in cancer treatment. It provides a classification of HDAC inhibitors based on their structural attributes, and addresses HDAC-induced cytotoxicity.. Lastly, it discusses and assesses the rationale behind therapies that combine HDAC inhibitors with other anticancer agents to treat solid tumors. Given its scope, it offers a valuable resource for all researchers, clinicians, and students working in formulation, drug discovery, oncology, and personalized medicine.
Calcium Binding Proteins in Normal and Transformed Cells
Proceedings of the First European Symposium held in Brussels, Belgium, April 20--22, 1989
