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Chemistry at Interfaces
Chemistry at Interfaces provides an introduction to the fundamental concepts in interfacial chemistry. It aims to provide students and research workers who have not had training in a school of surface chemistry with the means to set up and use interfacial techniques and to interpret measurements. For this reason, more emphasis is given to experimental details and to the associated pitfalls than most other books in the field. The book begins by considering some of the basic laws governing behavior in chemical systems and how these apply to some examples of interfacial processes. This is followed by a discussion of two specific properties oSf interfaces: the tendency to concentrate reactants and the ability to orientate molecules, thus increasing their reactivity. Separate chapters cover standards of cleanliness in interfacial work and methods to achieve them; techniques for the study of interfacial films; the kinetics of physical processes that can occur at an interface; and chemical and biological processes and reactions. The final chapter provides an overview of the wide-ranging applications of interfacial chemistry to practical problems.
Lipases and Phospholipases in Drug Development
Lipases and Phospholipases are key control elements in mammalian metabolism. They share many common features that set them apart from other metabolic enzyme classes, most importantly their association with biological membranes. Their potential as drug targets for the treatment of metabolic diseases is widely recognized, and the first lipase inhibitor drugs have been successfully introduced. Providing drug developers with a firm foundation for lipase-centered drug design, the editors of this volume have assembled experts from different scientific disciplines to create a comprehensive handbook for all pharmaceutical chemists, biochemists and physiologists working with lipases. The authors examine fundamental aspects of lipase function in vitro and in vivo, explaining how this knowledge may be used to develop lipase assays. They also treat the physiological roles of lipases in normal and disordered metabolism, as well as strategies to target lipases for the treatment of diabetes, obesity and related disorders. Additional topics include the application of phospholipases for liposome-based drug delivery and their use as diagnostic tools.
Handbook of Thin Films, Five-Volume Set
This five-volume handbook focuses on processing techniques, characterization methods, and physical properties of thin films (thin layers of insulating, conducting, or semiconductor material). The editor has composed five separate, thematic volumes on thin films of metals, semimetals, glasses, ceramics, alloys, organics, diamonds, graphites, porous materials, noncrystalline solids, supramolecules, polymers, copolymers, biopolymers, composites, blends, activated carbons, intermetallics, chalcogenides, dyes, pigments, nanostructured materials, biomaterials, inorganic/polymer composites, organoceramics, metallocenes, disordered systems, liquid crystals, quasicrystals, and layered structures. Thi...
Engineering Of/with Lipases
The innovative uses of lipases in a wide variety of organic syntheses and the modification of existing fats and oils have increased exponentially over the last five years, due to the increasing availability of lipases from (genetically engineered) microbial sources, coupled with their special capacity to act as catalysts at hydrophilic/hydrophobic interfaces. As a result of the structural characterisation performed during the same period, applications of these lipases can now be developed in a much more rational way. Engineering of/with Lipases presents two major topics: the design and production of lipases with desired, preselected properties, and the use of lipases for desired applications...
Molecular Dynamics of Biomembranes
Protein insertion and translocation, intracellular traffic and sorting of membranes and their components, and lipid-protein interactions were the main topics of the Advanced Study Institute on "Molecular Dynamics of Membranes", which was held in June 1995 in Cargese, Corsica, France. The course, co-sponsored by NATO and FEBS, was the fifth in a series that started in 1987 and takes place every two years in the Institut d'Etudes Scientifiques in Cargese. This Institute, ideally situated and fully equiped for this type of scientific meeting has greatly contributed to the great success of the courses. Of course, also the outstanding contributions of a large number of well known scientists and t...
Vesicles
"Offers a concise, logically organized survey of vesicular science and the practical applications of vesicles--including the latest advances in drug delivery. Contains over 2500 helpful citations to the literature, more than 220 drawings and photographs, many in color, and some 350 equations. Presents important topics that indicate the current scope and direction of vesicular research."
Lipid Biotechnology
This text presents the latest advances in supercritical fluid technology, biocatalysis, bioprocess engineering, and crop breeding. It offers an in-depth review of the most recent principles and approaches utilized in the development and design of lipids for cosmetic, industrial and pharmaceutical, and food products. Discussing a variety of lipid-ac
Intestinal Lipid Metabolism
This book was stimulated by the enthusiasm shown by attendees at the meetings in Saxon River, VT, sponsored by the Federation ofAmerican Societies for Experimental Biology (FASEB), on the subject of the intestinal processing of lipids. When these meetings were first started in 1990, the original organizers, two of whom are editors ofthis volume (CMM and PT), had two major goals. The first was to bring together a diverse group ofinvestiga tors who had the common goal of gaining a better understanding of how the intestine ab sorbs lipids. The second was to stimulate the interest of younger individuals whom we wished to recruit into what we believed was an exciting and fruitful area ofresearch....
