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The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 1-2696 presented on April 17-18, 2016, at the AACR Annual Meeting.
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What have we discovered about performance practice in the Sam Wanamaker Playhouse since the opening of the intimate candlelit theatre at Shakespeare's Globe? Playing Indoors reveals the results of a two-year study into the performance of Elizabethan and Jacobean drama in this unique theatre, drawing together insights into early modern stage practice and the observations of today's actors and spectators. A history of the experiences of artists and audience members who experienced the space first, the book is also a study of the significance of re-imagined theatres like the Sam Wanamaker Playhouse and the Globe. Accessibly written and intended for a wide audience of students, scholars, artists and theatre-goers, Playing Indoors is a valuable contribution to the young field of early modern practice-as-research.
Cancer cell biology research in general, and anti-cancer drug development specifically, still relies on standard cell culture techniques that place the cells in an unnatural environment. As a consequence, growing tumor cells in plastic dishes places a selective pressure that substantially alters their original molecular and phenotypic properties.The emerging field of regenerative medicine has developed bioengineered tissue platforms that can better mimic the structure and cellular heterogeneity of in vivo tissue, and are suitable for tumor bioengineering research. Microengineering technologies have resulted in advanced methods for creating and culturing 3-D human tissue. By encapsulating the...