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First multi-year cumulation covers six years: 1965-70.
Sepsis is a serious condition that is associated with high mortality despite advanced modern medical treatment. Recent years have witnessed novel paradigms describing host responses in sepsis. In particular, the delicate balance between pro- and anti-inflammatory reactions has been subject to intense research. This volume in the book series 'Contributions to Microbiology' presents the state of the art in this rapidly expanding field of research. Leading international experts have contributed with reviews on the most relevant topics in the field such as clinical aspects, pathways of sepsis and pro- and anti-inflammatory mechanisms as well as their regulation. The book will be a valuable source of up-to-date information for clinicians, microbiologists, immunologists, and students with an interest in the complex regulation of host responses during microbial sepsis.
First multi-year cumulation covers six years: 1965-70.
Anesthesia and the Lung 1992 presents recent advances in the diagnosis, pre-, intra-, and postoperative anesthetic management of patients with lung disease, presenting for pulmonary and non-pulmonary surgery. It also deals with ventilation-perfusion issues, the lung as a metabolic organ, the effects of anesthesia on pulmonary mechanics and pulmonary blood flow. In addition, there are chapters that focus on hypoxia; regional differences in the lung; pulmonary surfactant; recent advances in the understanding of pulmonary edema; high altitude disease; anesthesia and the control of breathing; recent development in oximetry; instrumentation designed to measure pulmonary oxygen tension, pO2 and pCO2 transcutaneously; differential lung ventilation; reactive airways; septic shock; the adult respiratory distress syndrome and numerous aspects of ventilatory support.
Much research over the past 30 to 40 years has shown that the inflammatory response, while critical for host defense during microbial infection, may itself play a central role in the pathogenesis of sepsis. Although key mediators responsible for this injury have been identified, efforts clinically to augment our conventional antimicrobial and supportive therapies during sepsis with agents modulating the inflammatory response have been unsuccessful. As a result, the mortality associated with this lethal syndrome, especially when complicated by shock, has remained persistently high. Unfortunately, during this same period of time, the incidence of sepsis has accelerated as other fields of medicine have relied increasingly on therapies that predispose to infection. While frustrating, overall this experience in the field of sepsis has not been without value. Most importantly, it has helped define on several different levels the complexity of the septic patient. Recognizing and addressing this complexity as discussed by each of the contributors to Evolving Concepts in Sepsis and Septic Shock may now provide new inroads into the treatment of sepsis.
Theodore H. Stanley, M. D. Anesthesia and the Lung contains the Refresher Course manuscripts of the presentations of the 34th Annual Postgraduate Course in Anesthesiology which took place at The Cliff Conference Center in Snowbird, Utah, February 17-21, 1989. The chapters reflect recent advances in the diagnosis, pre-, intra-, and postoperative anesthetic management of patients with lung disease, presenting for pulmonary and non-pulmonary surgery. They also deal with ventilation-perfusion issues, the lung as a metabolic organ, the effects of anesthesia on pulmonary mechanics and pulmonary blood flow. In addition there are chapters that will focus around hypoxia; regional differences in the l...
The Third Edition of this definitive reference provides comprehensive guidelines on the diagnosis, treatment, and prevention of every infectious disease seen in current clinical practice. More than 300 world-class practitioners detail the full range of clinical infections, microorganisms, diagnostic tests, and antimicrobial therapies. Coverage includes chapters on surgical infections written by preeminent surgeons and up-to-the-minute information on HIV infection. A comprehensive antimicrobial drugs section includes tables that provide at-a-glance prescribing information. New Third Edition chapters cover bioterrorism, hospital infections, emerging infections, human herpesvirus-8, West Nile virus, food safety, linezolid and quinupristin/dalfopristin, molecular diagnostics, and diagnostic significance of nonspecific laboratory abnormalities.
A compilation of stories, essays, and poems originally published from the On Being a Doctor, On Being a Patient, and Ad Libitum sections of Annals of Internal Medicine.
Includes field staffs of Foreign Service, U.S. missions to international organizations, Agency for International Development, ACTION, U.S. Information Agency, Peace Corps, Foreign Agricultural Service, and Department of Army, Navy and Air Force