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Handbook of Neural Activity Measurement
Underlying principles of the various techniques are explained, enabling neuroscientists to extract meaningful information from their measurements.
Functional Brain Mapping: Methods and Aims
This book provides an essential overview of the broad range of functional brain imaging techniques, as well as neuroscientific methods suitable for various scientific tasks in fundamental and clinical neuroscience. It also shares information on novel methods in computational neuroscience, mathematical algorithms, image processing, and applications to neuroscience. The mammalian brain is a huge and complex network that consists of billions of neural and glial cells. Decoding how information is represented and processed by this neural network requires the ability to monitor the dynamics of large numbers of neurons at high temporal and spatial resolution over a large part of the brain. Functional brain optical imaging has seen more than thirty years of intensive development. Current light-using methods provide good sensitivity to functional changes through intrinsic contrast and are rapidly exploiting the growing availability of exogenous fluorescence probes. In addition, various types of functional brain optical imaging are now being used to reveal the brain’s microanatomy and physiology.
Integrins
An integrin, or integrin receptor, is an integral membrane protein in the plasma membrane of cells. It plays a role in the attachment of a cell to the extracellular matrix (ECM) and to other cells, and in signal transduction from the ECM to the cell. There are many types of integrin, and many cells have multiple types on their surface. Integrins are of vital importance to all metazoans, from humans to sponges. This volume in Methods in Enzymology presents methods for studying integrins.
Essentials of Cognitive Neuroscience
Essentials of Cognitive Neuroscience guides undergraduate and early-stage graduate students with no previous neuroscientific background through the fundamental principles and themes in a concise, organized, and engaging manner. Provides students with the foundation to understand primary literature, recognize current controversies in the field, and engage in discussions on cognitive neuroscience and its future Introduces important experimental methods and techniques integrated throughout the text Assists student comprehension through four-color images and thorough pedagogical resources throughout the text Accompanied by a robust website with multiple choice questions, experiment vidoes, fMRI data, web links and video narratives from a global group of leading scientists for students. For Instructors there are sample syllabi and exam questions
In Vivo Optical Imaging of Brain Function, Second Edition
These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques. New in the Second Edition: Voltage-sensitive dyes imaging in awake behaving animals Imaging based on genetically encoded probes Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping Using pH-sensitive dyes for fu...
Cerebral Cortex
Volume 10 is a direct continuation and extension of Volume 3 in this series, Visual Cortex. Given the impressive proliferation of papers on visual cortex over the intervening eight years, Volume 10 has specifically targeted visual cortex in primates and, even so, it has not been possible to survey all of the major or relevant developments in this area. Some research areas are experiencing rapid change and can best be treated more comprehensively in a subsequent volume; for example, elaboration of color vision; patterns and subdivisions of functional columns. One major goal of this volume has been to provide an overview of the intrinsic structural and functional aspects of area 17 itself. Con...
Sleep
An estimated 40 million Americans and millions of others worldwide suffer from some type of sleep disruption or disorder, and these numbers are rapidly increasing. As biomedical technologies advance our understanding of sleep, a wave of developments in sleep research and the emergence of new technologies offer hope and help for a good night’s sleep. Sleep: Circuits and Functions discusses the major discoveries related to the circuits responsible for slow wave sleep, REM sleep, narcolepsy, and the possible role of sleep in memory and developmental processes. World-renowned researcher Pierre-Hervé Luppi and a panel of expert contributors highlight advances in sleep research obtained by means of promising technologies. Data obtained by differential gene expression analysis, transgenic mice, and functional imaging is presented, as well as theoretical concepts on the mechanisms regulating sleep. Updating our knowledge of the strides made in sleep research, this comprehensive book also identifies future research opportunities in this growing field. It is an essential resource for medical professionals and researchers who aim to finally put sleep disorders to bed.
Itch
Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direc
The Neural Bases of Multisensory Processes
It has become accepted in the neuroscience community that perception and performance are quintessentially multisensory by nature. Using the full palette of modern brain imaging and neuroscience methods, The Neural Bases of Multisensory Processes details current understanding in the neural bases for these phenomena as studied across species, stages
Dopamine - Glutamate Interactions in the Basal Ganglia
The basal ganglia are involved in complex brain functions, from voluntary movement control to learning and reward processing, and they are implicated in numerous neurological and psychiatric disorders. Information from the cerebral cortex and thalamus is conveyed to basal ganglia nuclei via glutamate release, while dopamine from the midbrain is rel
