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Throughout most of history, medicinal plants and their active metabolites have represented a valuable source of compounds used to prevent and to cure several diseases. Interest in natural compounds is still high as they represent a source of novel biologically/pharmacologically active compounds. Due to their high structural diversity and complexity, they are interesting structural scaffolds that can offer promising candidates for the study of new drugs, functional foods, and food additives. Plant extracts are a highly complex mixture of compounds and qualitative and quantitative analyses are necessary to ensure their quality. Furthermore, greener methods of extraction and analysis are needed today. This book is based on articles submitted for publication in the Special Issue entitled “Qualitative and Quantitative Analysis of Bioactive Natural Products” that collected original research and reviews on these topics.
This book represents one of the most up-to-date collections of articles on clinical practice and research in the field of Autism Spectrum Disorders (ASD). The scholars who contributed to this book are experts in their field, carrying out cutting edge research in prestigious institutes worldwide (e.g., Harvard Medical School, University of California, MIND Institute, King’s College, Karolinska Institute, and many others). The book addressed many topics, including (1) The COVID-19 pandemic; (2) Epidemiology and prevalence; (3) Screening and early behavioral markers; (4) Diagnostic and phenotypic profile; (5) Treatment and intervention; (6) Etiopathogenesis (biomarkers, biology, and genetic, ...
This special issue of the European Journal of Cognitive Psychology focuses on spatial congruency effects. The dominant view that has emerged after 50 years of research on this topic is that an automatic route processes task-irrelevant spatial information, while another, controlled, route supports rule-based response activation. However, in line with recent literature, this issue reports studies that show that what has been considered automatic, is in fact subject to various control processes. Consequently, in order to account successfully for congruency effects, dual-route models should be adapted so that they can account for between- and within-trial modulation of congruency effects. On the...
Innate immunity is one the most evolutionally conserved systems, designed to protect the organism from viruses and bacterial infections, stress and many other types of attacks from the outside world. During the past decade, the capacity of molecular biology and information technology to produce and analyse data have grown exponentially, rapidly reforming many aspects of immunology research in the post-genomics era. As a result, scientific understanding of signalling networks governing the innate immunity response in human tissues and other organisms has evolved beyond recognition, compared to even just a decade ago. Many strategies have been designed over the years to identify novel proteins...
Plant-parasitic nematodes (PPNs) devastate many crop plants, causing billions of dollars in agricultural losses each year. Effective management methods to combat PPNs are synthetic nematicides, but most are non-specific and notoriously toxic and threaten the soil ecosystem, groundwater and human health. The plant by-products, such as oilseed cakes, are sources of bioactive compounds with nematicidal potential. Oilseed cakes are an excellent organic fertilizer, and their bioactive compounds are now gaining importance as they are safe for the environment. This book provides the most comprehensive and up-to-date review of research on the use of oilseed cakes against PPNs. The complete knowledge...
It can be reasonably anticipated that, over the next generations, the proportion of elderly people will remarkably increase and, with this, the number ofpersons suffering from acute (e.g. cerebral ischemia) or chronic neurodegenerative disorders. To date, approved drugs only alleviate the symptoms ofthese diseases (for instance, acetylcholinesterase inhibitors in Alzheimer disease and L-dopa and dopamine-agonists in Parkinson disease), while none seems to stop the progression of the degenerative processes underlying them. The development of effective preventive or protective therapies has been impeded by the limitations of our knowledge of the causes and the mechanisms by which neurons die i...
Revised, restructured and updated to reflect the latest data and debates, this new edition of the widely used, classic textbook offers students an accessible account of the major social divisions that structure social life. Written by internationally known sociologists and experts, the book: • addresses a wide range of social divisions and inequalities in novel ways, with added chapters on education and age; • provides a framework for understanding contemporary social inequalities and diversities, and how they interrelate; • lends itself to teaching in a range of contexts with the potential to dip into particular chapters for different modules, or to use the book in a more extensive way for one particular module; • features signposting through the material, as well as key points, discussion questions and selected further readings for each chapter. This clearly written volume presents a structured and critical guide to a core field that cuts across disciplines. It is an invaluable introduction and source book for students taking social inequalities and diversity modules in sociology, social policy, social work, education and health studies.
It is anticipated that by 2050 we will have nine billion people to feed-how can we manage? As scarcities of agricultural land, water, forest, fishery and biodiversity resources, as well as nutrients and nonrenewable energy are foreseen, insect rearing is one solution for food and feed security in the future. In this book, we have nine chapters ranging from mushroom, insect, and earthworm farming to smart packaging and 3D printing of future foods. However, because of their biological composition, several issues should be considered, such as microbial safety, toxicity, palatability, and the presence of inorganic compounds. Specific health implications ought to be kept in mind especially if mushrooms, earthworms, or insects are reared on waste products. Allergies induced through insects' ingestion also deserve attention. A possible HACCP plan has been described considering pre-requirements in insect production and transformation.
The development of the brain and nervous system is shaped not just by a genetic program, but also by the effects of multiple environmental stimuli. There are currently no book-length treatments of perinatal neurodevelopment. The proposed book seeks to fill this gap by presenting a collection of chapters from leading experts in the field. It is intended to be comprehensive and will cover all aspects of neurodevelopmental programming in lab animals and in human subjects. The third section of the book will look at ways of translating insights we have garnered from animal studies to human and clinical studies. The primary audience for this work is basic researchers interested in the effects of perinatal imprinting on the development of the nervous system and associated diseases.
This collection of selected chapters offers a comprehensive overview of state-of-the-art mathematical methods and tools for modeling and analyzing cancer phenomena. Topics covered include stochastic evolutionary models of cancer initiation and progression, tumor cords and their response to anticancer agents, and immune competition in tumor progression and prevention. The complexity of modeling living matter requires the development of new mathematical methods and ideas. This volume, written by first-rate researchers in the field of mathematical biology, is one of the first steps in that direction.