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Thoroughly revised and updated for the second edition, this comprehensive textbook integrates basic and advanced concepts of mechanics with numerical methods and biomedical applications. Coverage is expanded to include a complete introduction to vector and tensor calculus, and new or fully updated chapters on biological materials and continuum mechanics, motion, deformation and rotation, and constitutive modelling of solids and fluids. Topics such as kinematics, equilibrium, and stresses and strains are also included, as well as the mechanical behaviour of fibres and the analysis of one-dimensional continuous elastic media. Numerical solution procedures based on the Finite Element Method are presented, with accompanying MATLAB-based software and dozens of new biomedical engineering examples and exercises allowing readers to practise and improve their skills. Solutions for instructors are also available online. This is the definitive guide for both undergraduate and graduate students taking courses in biomechanics.
Thoroughly revised and updated for the second edition, this comprehensive textbook integrates basic and advanced concepts of mechanics with numerical methods and biomedical applications. Coverage is expanded to include a complete introduction to vector and tensor calculus, and new or fully updated chapters on biological materials and continuum mechanics, motion, deformation and rotation, and constitutive modelling of solids and fluids. Topics such as kinematics, equilibrium, and stresses and strains are also included, as well as the mechanical behaviour of fibres and the analysis of one-dimensional continuous elastic media. Numerical solution procedures based on the Finite Element Method are presented, with accompanying MATLAB-based software and dozens of new biomedical engineering examples and exercises allowing readers to practise and improve their skills. Solutions for instructors are also available online. This is the definitive guide for both undergraduate and graduate students taking courses in biomechanics.
This book gathers selected, extended and revised contributions to the 17th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering and the 5th Conference on Imaging and Visualization (CMBBE 2021), held online on September 7-9, 2021, from Bonn, Germany. It reports on cutting-edge models, algorithms and imaging techniques for studying cells, tissues and organs in normal and pathological conditions. It covers numerical and machine learning methods, finite element modeling and virtual reality techniques, applied to understand biomechanics of movement, fluid and soft tissue biomechanics. It also reports on related advances in rehabilitation, surgery and diagnosis. All in all, this book offers a timely snapshot of the latest research and current challenges at the interface between biomedical engineering, computational biomechanics and biological imaging. Thus, it is expected to provide a source of inspiration for future research and cross-disciplinary collaborations.
This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.
Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of...
Presents both current and future aspects of diagnosis and treatment. Presents evidence-based knowledge of pressure ulcer aetiology. Contains over 90 illustrations. Explores the possiblities of tissue repair using new tissue engineering strategies.
Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine addresses the key concepts involved in the interactions between cells and biomaterials in the musculoskeletal tissue engineering and regenerative medicine field. The updated developments and challenges of the mechanisms/mechanobiology and structure-function properties of those interactions, as well as emerging technologies underlying tissue-engineered scaffolding, are carefully discussed. Lastly, cell engineering and cell-based therapies, growth factors/drugs properties, vascularization, immunomodulation are also outlined. Given the large number of musculoskeletal disorders and related inju...
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Hydrogels represent one of the cornerstones in tissue engineering and regenerative medicine, due to their biocompatibility and physiologically relevant properties. These inherent characteristics mean that they can be widely exploited as bioinks in 3D bioprinting for tissue engineering applications as well as injectable gels for cell therapy and drug delivery purposes. The research in these fields is booming and this book provides the reader with a terrific introduction to the burgeoning field of injectable hydrogel design, bioprinting and tissue engineering. Edited by three leaders in the field, users of this book will learn about different classes of hydrogels, properties and synthesis strategies to produce bioinks. A section devoted to the key processing and design challenges at the hydrogel/3D bioprinting/tissue interface is also covered. The final section of the book closes with pertinent clinical applications. Tightly edited, the reader will find this book to be a coherent resource to learn from. It will appeal to those working across biomaterials science, chemical and biomedical engineering, tissue engineering and regenerative medicine.