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The book takes in consideration some dehydrogenases, enzymes with different functions in the cells by using different substrates, such as hydroxysteroid dehydrogenases, aldehyde dehydrogenases, glucose-6-phosphate dehydrogenase, pyruvate dehydrogenase complex, glutamate dehydrogenase, succinate dehydrogenase. They are examined from the following points of view: biochemistry, physiological functions and role in some diseases and in the development of tumours. For these reasons, the book is divided into three sections: 1. Dehydrogenases and cancer 2. Dehydrogenases and some diseases 3. Dehydrogenases and physiological role
Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using her...
Zoonoses, diseases transmitted from animals to humans, hold immense global significance, impacting public health, economies, and ecosystems. Adopting the One Health approach, which recognizes the interconnectedness of human, animal, and environmental health, is crucial in tackling these challenges. Zoonotic diseases pose significant public health threats. Diseases like rabies, Ebola, and influenza have claimed countless lives worldwide. Without proper management, these diseases can rapidly escalate into pandemics, as seen with the COVID-19 pandemic, originating from a zoonotic transmission. The health of humans and animals are intricately linked, making collaborative efforts essential for di...
Herpes simplex virus (HSV) infections comprise one of the most important health problems worldwide. HSV-1 and HSV-2 that are the types most frequently seen in disease, manifested by sores and blisters on the mouth, tongue, skin, and genitals of infected individuals. Moreover, herpetic infections can reach life-threatening levels; for instance, HSV-2 prevalence has increased greatly in human immunodeficiency virus-positive patients. This indicates that the herpetic infection could be a major cause of morbidity in immunosuppressed patients. Unfortunately, resistance against antiherpetic drugs has recently been reported. Therefore there is an immediate need to search for new antiviral agents in order to cope with HSV infections. Recently, it has been demonstrated that traditional medicinal plants have strong antiviral activity and some are already being used in the treatment of viral infections, including herpes simplex infections. Accordingly, this chapter aims to present published information on various herbal compounds, investigate the antiherpetic effectiveness of these compounds, and determine the potential of plants as herpetic treatments in the future.
Nanobiomaterials Science, Development and Evaluation examines the practical aspects of producing nanostructured biomaterials for a range of applications. With a strong focus on materials, such as metals, ceramics, polymers, and composites, the book also examines nanostructured coatings and toxicology aspects. Chapters in Part One look at materials classes and their synthesis with information on all major material groups. Part Two focuses on nanostructured coatings and practical aspects associated with the use of nanobiomaterials in vivo. This book brings together the work of international contributors who are actively engaged on the forefront of research in their respective disciplines, and is a valuable resource for materials scientists in academia, industry, and all those who wish to broaden their knowledge in the allied field. - Focuses on the synthesis and evaluation techniques for a range of nanobiomaterials - Examines nanostructured inorganic coatings for biomaterials - Discusses issues related to the toxicology of nanobiomaterials - Presents the practical aspects of nanobiomaterials
Nanobiomaterials: Nanostructured materials for biomedical applications covers an extensive range of topics related to the processing, characterization, modeling, and biomedical applications of nanostructured ceramics, polymers, metals, composites, self-assembled materials, and macromolecules. Novel approaches for bottom-up and top-down processing of nanostructured biomaterials are highlighted. In addition, innovative techniques for characterizing the in vitro behavior and in vivo behavior of nanostructured biomaterials are considered. Applications of nanostructured biomaterials in dentistry, drug delivery, medical diagnostics, surgery and tissue engineering are examined. - Provides a concise description of the materials and technologies used in the development of nanostructured biomaterials - Provides industrial researchers with an up-to-date and handy reference on current topics in the field of nanostructured biomaterials - Includes an integrated approach that is used to discuss both the biological and engineering aspects of nanostructured biomaterials
Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat
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