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Inflammasome Biology
Inflammasome Biology: Fundamentals, Role in Disease States, and Therapeutic Opportunities is a complete reference on the role of inflammasomes in health and disease. Sections cover the different types of inflammasomes, including cellular signaling, structural and evolutive aspects, overview the role of inflammasomes in key diseases, microbial infections and human body systems conditions, cover the interplay between Inflammasomes and cell death processes, and discuss current therapeutic opportunities driven by inflammasome research, including targeting, blocking and inhibiting the development of inflammasomes through both synthetic and natural compounds. This book is the perfect reference for cell biologists, immunologists and research clinicians to understand the foundations of inflammasomes and explore the therapeutic opportunities they present. Pharma researchers may also find this reference invaluable in devising new approaches to developing anti-inflammatory drugs. Provides comprehensive coverage of the subject of inflammasome biology Authored by leading experts worldwide Provides biological insights that have both health implications and therapeutic potential
Children of the Night
A vivid, brilliant, darkly humorous and horrifying history of some of the strangest dictators that Europe has ever seen. 'A witty and page-turning narrative full of grotesque characters' Misha Glenny 'Will leave you astonished, exhausted and curious... An unapologetic page turner' Spectator 'Essential reading for anyone interested in Romania past and present' John Simpson 'An engaging introduction to the rich history [of Romania]' New Statesman Balanced precariously on the shifting fault line between East and West, Romania's past is one of the great untold stories of modern Europe. The country that gave us Vlad Dracula, and whose citizens consider themselves descendants of ancient Rome, has ...
In The Shadow Of The Banyan
A stunning, powerful debut novel set against the backdrop of the Cambodian War, perfect for fans of Chris Cleave and Chimamanda Ngozi Adichie For seven-year-old Raami, the shattering end of childhood begins with the footsteps of her father returning home in the early dawn hours bringing details of the civil war that has overwhelmed the streets of Phnom Penh, Cambodia's capital. Soon the family's world of carefully guarded royal privilege is swept up in the chaos of revolution and forced exodus. Over the next four years, as she endures the deaths of family members, starvation, and brutal forced labour, Raami clings to the only remaining vestige of childhood - the mythical legends and poems to...
The Fishermen
In this striking novel about an unforgettable childhood, four Nigerian brothers encounter a madman whose mystic prophecy of violence threatens the core of their close-knit family Told by nine-year-old Benjamin, the youngest of four brothers, The Fishermen is the Cain and Abel-esque story of a childhood in Nigeria, in the small town of Akure. When their father has to travel to a distant city for work, the brothers take advantage of his absence to skip school and go fishing. At the forbidden nearby river, they meet a madman who persuades the oldest of the boys that he is destined to be killed by one of his siblings. What happens next is an almost mythic event whose impact-both tragic and redemptive-will transcend the lives and imaginations of the book's characters and readers. Dazzling and viscerally powerful, The Fisherman is an essential novel about Africa, seen through the prism of one family's destiny.
