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The Cold War reconsidered as a limited nuclear war “Inexorable clarity and care for his fellow humans mark Robert Jacobs's guide to the Cold War as a limited nuclear war, whose harms disfigure any possible future.”—Norma Field, author of In the Realm of a Dying Emperor: Japan at Century’s End In the fall of 1961, President Kennedy somberly warned Americans about deadly radioactive fallout clouds extending hundreds of miles from H‑bomb detonations, yet he approved ninety‑six US nuclear weapon tests for 1962. Cold War nuclear testing, production, and disasters like Chernobyl and Fukushima have exposed millions to dangerous radioactive particles; these millions are the global hibaku...
The rapid developments in molecular genetics have clarified many of the muta tions in monogenic thyroid diseases over the last two decades; now the target of molecular thyroid genetics has become the oligogenic thyroid diseases. These include the autoimmune thyroid diseases and familial thyroid cancers, both of which are much commoner than the monogenic diseases. However, the method ological approach to the genetics of these more complex diseases is still far from being well established. Although the discovery of susceptibility genes has been partially accomplished in complex diseases such as asthma, Crohn's dis ease, and types I and II diabetes mellitus, the elucidation of susceptibility ge...
Following the Great East Japan Earthquake on March 11, 2011, tsunamis engulfed the Fukushima Daiichi nuclear power plant located on Japan's Pacific Coast, leading to the worst nuclear disaster the world has seen since the Chernobyl crisis of 1986. Prior to this disaster, Japan had the third largest commercial nuclear program in the world, surpassed only by those in the United States and France—nuclear power significantly contributed to Japan's economic prosperity, and nearly 30% of Japan's electricity was generated by reactors dotted across the archipelago, from northern Hokkaido to southern Kyushu. This long period of institutional stasis was, however, punctuated by the crisis of March 11...
With cancer-related deaths projected to rise to 10.3 million people by 2020, the need to prevent, diagnose, and cure cancer is greater than ever. Cancer Imaging presents readers with the most up-to-date imaging instrumentation, general and diagnostic applications for various cancers, with an emphasis on lung and breast carcinomas--the two major worldwide malignancy types. This book discusses the various imaging techniques used to locate and diagnose tumors, including ultrasound, X-ray, color Doppler sonography, PET, CT, PET/CT, MRI, SPECT, diffusion tensor imaging, dynamic infrared imaging, and magnetic resonance spectroscopy. It also details strategies for imaging cancer, emphasizing the im...
The continuing AIDS pandemic reminds us that despite the unrelenting quest for knowledge since the early 1980s, we have much to learn about HIV and AIDS. This terrible syndrome represents one of the greatest challenges for science and medicine. The purpose of this book is to aid clinicians, provide a source of inspiration for researchers, and serve as a guide for graduate students in their continued search for a cure of HIV. The first part of this book, "From the laboratory to the clinic," and the second part, "From the clinic to the patients," represent the unique but intertwined mission of this work: to provide basic and clinical knowledge on HIV/AIDS.
After a major disaster, when investigators are piecing together the story of what happened, a striking fact often emerges: before disaster struck, some people in the organization involved were aware of dangerous conditions that had the potential to escalate to a critical level. But for a variety of reasons, this crucial information did not reach decision-makers. So, the organization moved ever closer to catastrophe, effectively unaware of the possible threat—despite the fact that some of its employees could see it coming. What is the problem with communication about risk in an organization, and why does this problem exist? What stops people in organizations or project teams from freely rep...
Thyroid Diseases: Clinical Fundamentals and Therapy provides a wide-ranging examination of all clinically significant areas of thyroid diseases. Underlying physiological principles are closely linked to the clinical situation and practical therapeutic interventions. The book examines the clinical course, therapy, and final outcome of thyroid diseases, particularly the bimodal and transient evolution of several thyroid diseases. It also discusses the medical, surgical, and radiometabolic therapy of thyroid diseases, stressing the pros and cons of each therapeutic modality. More than 80 acknowledged experts from North America, Europe, and Japan have contributed to this exceptional reference volume, making it essential for physiologists, clinical endocrinologists, radiologists, researchers in nuclear medicine, oncologists, and radiotherapists.
The current age of clinical medicine is witnessing biotechnological innovation at an unprecedented pace. As a result, the recently popularized clinical practice guidelines (CPG), as a tool to assist clinical decision-making, have been struggling to keep up. Thyroid Cancer: From Emergent Biotechnology to Clinical Practice Guidelines rides the wave o
This book is a comprehensive, easy-to-read discussion of the organ-specific autoimmune endocrine diseases emphasizing new contributions and trends for research and management. It begins with a brief chapter introducing the general principles of immunology, followed by discussions covering topics such as immunogenetics and animal models and how they can be applied toward interpreting human autoimmune endocrine diseases, autoimmune thyroid diseases, insulin-dependent diabetes mellitus hypophysitis, and Addison's disease. The book also discusses future trends toward gaining an understanding of these disorders and possible therapeutic principles. It is well-illustrated and will prove to be a useful reference source for internists, endocrinologists, and postgraduate students interested in human autoimmune endocrine diseases.