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Mayo Clinic Cases in Neuroimmunology
Mayo Clinic Cases in Neuroimmunology delivers a case-based walk-through of demyelinating, autoimmune, and other inflammatory neurologic disorders and their mimics. The authors present cases from their own extensive experience with common and rare neuroimmunologic disorders. This new addition to the Mayo Clinic Scientific Press series is a comprehensive volume on neuroimmunology that will stimulate and inform those aiming for clinical mastery.
Paraneoplastic Neurologic Disorders
This book extensively reviews Paraneoplastic Neurological Syndromes in light of the most recent descriptions of autoantibodies against neuronal cell surface antigens (only partly associated with paraneoplastic disorders) and the introduction of new immuno-oncological drugs that can contribute to causing diseases that are pathogenetically indistinguishable from paraneoplastic syndromes. These two new developments have not been addressed in other volumes available on the market. Section 1 focuses on immunological defense mechanisms against tumors. Besides investigating the pathogenetic mechanisms of these disorders, this section will also explore what the introduction of new drugs used in immu...
Neuroimmunology
This book provides a clinical focus on neuroinflammatory diseases as well as a review in pathophysiology and treatment approaches. Organized into six parts, the book begins with a basic review of the immune system and concepts for learning and treating neuroimmune conditions. The next four sections cover specific subfields of neuroimmunology and autoimmune neurology - the clinical and diagnostic features of multiple sclerosis, other autoimmune conditions of the central nervous system, autoimmune conditions of the peripheral nervous system, and systemic autoimmune conditions that affect the nervous system. To conclude, Section six discusses various clinical approaches to specific presentation...
MOGAD, Current Knowledge and Future Trends
Myelin oligodendrocyte glycoprotein (MOG) antibody disease (MOGAD) is a neurological, immune-mediated disorder targeting MOG protein, located on the outermost myelin sheaths in the central nervous system. The diagnosis is confirmed when serum MOG antibody is found in patients in the context of inflammatory attacks of the central nervous system, usually with the brain, brainstem, optic nerve, and spinal cord. Although MOGAD manifestations can fulfill diagnostic criteria for Neuromyelitis optica disorder (NMOSD), evidence suggests that they have distinct immunological mechanisms. Similar to NMOSD, patients with persistent MOG antibodies are at risk for recurrent events. Recovery of MOGAD is generally reasonable. However, some patients get disability after a severe acute attack. Treatment for an acute attack is typically intravenous high-dose steroids, plasma exchange (PLEX), or intravenous immunoglobulin (IVIG). Maintenance therapy with immunosuppressants, i.e., azathioprine, mycophenolate, rituximab, etc., usually prevents future attacks, although they have long-term side effects. Therefore, it is still controversial how long treatment should be continued.
Reusing Online Resources
This unique book outlines approaches to sharing and reusing resources for sustainable e-learning.
Neuro-Immuno-Gastroenterology
This book addresses important issues regarding the interaction between the nervous system, the immune system, and the digestive system. Gut flora has a profound influence on the shaping of the immune response, not only in the gastrointestinal system but also in the nervous system. Fascinatingly, manipulation of intestinal immune responses can be used to modulate neurological disease. Conversely, the nervous system and the psyche have significant effects on the functioning of the gut and liver. After introductory chapters on the neurology, the immunology and microbiology of the gut, the effects of the gut immune system and gut flora and its manipulation on neurological disease are discussed, followed by molecular mimicry and immune tolerance in neuroimmune diseases. Additionally, several chapters deal with gastrointestinal manifestations of neurological diseases. Neuro-Immuno-Gastroenterology is aimed at neurologists, gastroenterologists, and immunologists.
Marsden's Book of Movement Disorders
Marsden's Book of Movement Disorders covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more common conditions such as Parkinson's Disease through to very rare conditions such as Niemann-Pick disease.
Peripheral Neuropathy
Healing and symptom relief from an expert in treating this debilitating and dangerous condition. Nearly one in fifteen people—that's 20 million people in the United States—suffers from peripheral neuropathy, or nerve damage. Caused by such conditions as diabetes, cancer, vitamin deficiencies, and kidney disease as well as certain drugs and toxins, neuropathy brings numbness, tingling, and burning in the feet, legs, and fingertips. Neuropathy can be more than uncomfortable—it can be disabling: people whose fingertips are numb may find it hard to button clothing and complete other everyday tasks. Neuropathy is often dangerous, as well: people who cannot feel their feet are more likely to...
