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Biosynthesis of Heterocycles
This book describes biosynthetic methods to synthesize heterocyclic compounds, offering a guide for the development of new drugs based on natural products. The authors explain the role of natural products in chemistry and their formation along with important analytical methods and techniques for working with heterocycles. • Covers methods and techniques: isotopic labelling, enzymes and mutants, and pathway identification • Provides a thorough resource of information specifically on heterocyclic natural products and their practical biosynthetic relevance • Explains the role of natural products in chemistry and their formation • Discusses gene cluster identification and the use of biogenetic engineering in pharmaceutical application
Droplets and Sprays: Simple Models of Complex Processes
This book acts as a guide to simple models that describe some of the complex fluid dynamics, heat/mass transfer and combustion processes in droplets and sprays. Attention is focused mainly on the use of classical hydrodynamics, and a combination of kinetic and hydrodynamic models, to analyse the heating and evaporation of mono- and multi-component droplets. The models were developed for cases when small and large numbers of components are present in droplets. Some of these models are used for the prediction of time to puffing/micro-explosion of composite water/fuel droplets — processes that are widely used in combustion devices to stimulate disintegration of relatively large droplets into smaller ones. The predictions of numerical codes based on these models are validated against experimental results where possible. In most of the models, droplets are assumed to be spherical; some preliminary results of the generalisation of these models to the case of non-spherical droplets, approximating them as spheroids, are presented.
