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Brain Computation as Hierarchical Abstraction
An argument that the complexities of brain function can be understood hierarchically, in terms of different levels of abstraction, as silicon computing is. The vast differences between the brain's neural circuitry and a computer's silicon circuitry might suggest that they have nothing in common. In fact, as Dana Ballard argues in this book, computational tools are essential for understanding brain function. Ballard shows that the hierarchical organization of the brain has many parallels with the hierarchical organization of computing; as in silicon computing, the complexities of brain computation can be dramatically simplified when its computation is factored into different levels of abstrac...
Dendritic spines: from shape to function
One fundamental requisite for a comprehensive view on brain function and cognition is the understanding of the neuronal network activity of the brain. Neurons are organized into complex networks, interconnected through synapses. The main sites for excitatory synapses in the brain are thin protrusions called dendritic spines that emerge from dendrites. Dendritic spines have a distinct morphology with a specific molecular organization. They are considered as subcellular compartments that constrain diffusion and influence signal processing by the neuron and, hence, spines are functional integrative units for which morphology and function are tightly coupled. The density of spines along the dend...
High-Resolution Imaging of Cellular Proteins
This volume presents authoritative and cutting-edge methods and protocols focusing on three tool boxes covering the increasingly diverse methodologies used to image selected proteins and to investigate their function by light and electron microscopy. The first tool box includes the development of a wide range of molecular and immunological probes to target specific proteins. The second details the use of these probes for high resolution fluorescence microscopy and the third focuses on applications for transmission and scanning electron microscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls thus ensuring successful results in the further study of this vital field.
Immunoelectron Microscopy
Immunoelectron microscopy is a key technique that bridges the information gap between biochemistry, molecular biology, and ultrastructural studies placing macromolecular functions within a cellular context. In Immunoelectron Microscopy: Methods and Protocols, expert researchers combine the tools of the molecular biologist with those of the microscopist. From the molecular biology toolbox, this volume presents methods for antigen production by protein expression in bacterial cells, methods for epitope tagged protein expression in plant and animal cells allowing protein localization in the absence of protein specific antibodies as well as methods for the production of anti-peptide, monoclonal,...
Fisheries Review
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Graduate Programs in the Biological Sciences 2008
The six volumes of Peterson's Annual Guides to Graduate Study, the only annually updated reference work of its kind, provide wide-ranging information on the graduate and professional programs offered by accredited colleges and universities in the United States and U.S. territories and those in Canada, Mexico, Europe, and Africa that are accredited by U.S. accrediting bodies. Books 2 through 6 are divided into sections that contain one or more directories devoted to individual programs in a particular field. Book 3 contains more than 4,000 programs of study in 53 disciplines of the biological sciences.
The Five Senses and Beyond
How do our human senses work and help us interact with our surroundings, and what happens when these senses malfunction or are impaired? This book provides in-depth information that answers these questions and more. The Five Senses and Beyond: The Encyclopedia of Perception supplies students and general readers with accurate, up-to-date information about the human senses. It explains the "big five" senses in detail as well as lesser-known but important senses—perceptions such as balance, kinesthesia, temperature, and pain. After a helpful introduction, this reference work provides A-to-Z, cross-referenced entries on hundreds of topics in the realm of human perception that allow students to find and digest information quickly and draw connections between related topics. Through the use of activity sidebars, readers will also be able to explore the workings of the senses firsthand, lending an element of interactivity to this accessible encyclopedia. A convenient end-of-volume glossary provides definitions of unfamiliar terms.
