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Pathogenesis of Wound and Biomaterial-Associated Infections
Despite the recent advances in medical treatment, patients suffering from wounds such as burns or receiving surgical implants are still in great danger of infection. This has called attention to the need for better understanding of infections at the molecular level. Scientists from various disciplines summarize our knowledge today and investigate how methods to avoid wound and biomaterial-associated infections can be developed. These methods include new antibiotics, surgical strategies to prevent infection, and ways to stimulate the immune system and the tissue healing process. Specific topics include: the definition of microbial cell surface determinants important for adhesion to graft; the definition of extracellular bacterial enzymes and toxins involved in tissue breakdown and the local spread of infection; the prevention of the systemic spreading of infection with immunoglobulins and antibiotics; and the problem of multiple antibiotic resistance in most versatile pathogens.
The Molecular Immunology of Complex Carbohydrates
During the past three decades, the sugar moiety of complex carbohydrates has been found to be involved in important interactions of immunological specificity of antigens and to participate in a variety of cellular functions. The long polysaccharide side chains of the lipopolysaccharides on the outer membrane of Gram negative organisms provide surface antigens for differential serodiagnosis. Bacterial surface lectins are important in mediating the attachment of bacteria to host cells in the of infectious diseases. The carbohydrate pathogenesis moieties of cell surface glycoconjugates (glycoproteins and glycolipids) of mammals are the sites for intercellular recognition and for the regulatory ...
Handbook of Prebiotics and Probiotics Ingredients
While there is little dispute that probiotics and prebiotics, alone and together, have been proven to promote gastrointestinal health and proper immune function, the challenge faced by researchers is finding not only the right combinations, but also finding those that are fully compatible with the formulation, processing, packaging, and distributio
Microorganisms in Foods 5
The aim of this book is to assemble detailed information relating to foodborne pathogens in order to make it readily accessible to those who wish to employ the HACCP system for the control of microbial hazards. The book is concerned solely with foodborne pathogens and does not discuss spoilage organisms. Each chapter provides a general survey of a foodborne pathogen, with appropriate referencing to authoritative review material. Reviews the history and the occurrence of the organism in nature as well as its taxonomy. Discusses the symptoms (but not the treatment) of the relevant foodborne disease syndrome(s), as well as the mechanism of pathogenicity. Consideration is given to the available ...
The Innovation and Evolution of Medical Devices
This text provides a central resource for physicians, entrepreneurs, and the MBA students about how innovation occurs in medical device industry. The book uses the rise and fall of vaginal mesh kits to highlight the evolution of responses by the physicians, patients and the regulatory bodies. There are specific chapters reviewing the US regulatory issues and business practices that were consequential to withdrawal of most vaginal mesh kits from the US market. The book is meant to be concise, evidence-based, and practical for the first time readers to understand the innovation forces. Concise textual information from acknowledged experts is complemented by high-quality diagrams and images to ...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Bacterial Toxins and Cell Membranes
Advances in the purification of some bacterial protein toxins; Bacterial endotoxins and cell membranes; Mode of action of membrane-damaging toxins produced by Staphylococci; Thiol-activated (oxygen-labile) cytolysins; Biological effects of staphylococcal and streptococcal toxins; The interaction of bacterial products with the structure and function of the mammalian mitochondrion; Streptolysis S-forming and antitumour activities of group A streptococci; Seven toxic peptides that cross cell membranes; Cholera toxin and the cell membrane; Bacterial phospholipses.
The Genus Yersinia:
The 9th International Symposium on Yersinia was held in Lexington, Kentucky, USA on October 10-14, 2006. Over 250 Yersinia researchers from 18 countries gathered to present and discuss their research. In addition to 37 oral presentations, there were 150 poster presentations. This Symposium volume is based on selected presentations from the meeting and contains both reviews and research articles. It is divided into six topic areas: 1) genomics; 2) structure and metabolism; 3) regulatory mechanisms; 4) pathogenesis and host interactions; 5) molecular epidemiology and detection; and 6) vaccine and antimicrobial therapy development. Consequently, this volume covers a wide range of current research areas in the Yersinia field.
