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Synthetic biology is enabling scientists to use engineered genetic circuits in the cells as the basis for the development of new living therapeutics and as a powerful new weapon in the fight against diseases, especially cancer. Bacteria-mediated therapy is a promising alternative cancer treatment. The book covers the recent developments of cellular therapies from a synthetic biology perspective including engineered microbial therapies, CAR-T therapies etc. and is an indispensable guide to scientists in both biotechnology and medicine.
Second volume of a 40-volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about UV-visible and photoluminescence spectroscopy for the characterization of nanomaterials. Modern applications and state-of-the-art techniques are covered and make this volume essential reading for research scientists in academia and industry in the related fields.
This detailed volume introduces different methods to assess the structure and folding of bacterial amyloids and analyze their functions, either in vitro or in vivo. Despite their initial association with neurodegenerative diseases, there is now increasing evidence of alternative roles for amyloids, with beneficial aspects for cells. In particular, prokaryotes use amyloids as functional assemblies, where they are key players in the cell's physiology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Bacterial Amyloids: Methods and Protocols is an ideal guide for experts and novices alike to further explore these crucial protein assemblies.
Biological and chemical warfare agents, including viruses, bacteria, and explosive and radioactive compounds, can induce illness or death in humans, animals, and plants. Plasmonic nanosensors as detection tools of these agents offer significant advantages, including rapid detection, sensitivity, selectivity, and portability. This book explores novel and updated research on different types of plasmonic nanosensors for analysis of biological and chemical threat agents. It covers a brief theory of plasmonic nanosensors, summarizes the state-of-art in the molecular recognition of biological and chemical threat agents, and describes the application of various types of nanosensors in the detection...
Nanotechnology has the potential to solve many unmet, urgent healthcare requirements. However, bridging the translational gap between lab and clinic for nanodrugs is still challenging, and there is limited guidance on regulatory-relevant information and approaches. The main aim of this book is to provide guidance on characterization of drug carrier properties and efficacy required for regulatory acceptance of nanomaterials for their use in medicine.This book provides a comprehensive overview of drug loading and delivery nanocarriers, including their characteristics, methodologies and techniques to evaluate the association and interaction of the drug with different nanocarriers.
New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a...
Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine discusses recent advances in science and technology using nanoscale units that show the novel concept of combining nanotechnology with various research disciplines within both the biomedical and medicine fields. Self-assembly of molecules, macromolecules, and polymers is a fascinating strategy for the construction of various desired nanofabrication in chemistry, biology, and medicine for advanced applications. It has a number of advantages: (1) It is involving atomic-level modification of molecular structure using bond formation advanced techniques of synthetic chemistry. (2) It draws from the enormo...
This 21st Century Nanoscience Handbook will be the most comprehensive, up-to-date large reference work for the field of nanoscience. Handbook of Nanophysics, by the same editor, published in the fall of 2010, was embraced as the first comprehensive reference to consider both fundamental and applied aspects of nanophysics. This follow-up project has been conceived as a necessary expansion and full update that considers the significant advances made in the field since 2010. It goes well beyond the physics as warranted by recent developments in the field. Key Features: Provides the most comprehensive, up-to-date large reference work for the field. Chapters written by international experts in th...
This 21st Century Nanoscience Handbook will be the most comprehensive, up-to-date large reference work for the field of nanoscience. Handbook of Nanophysics by the same editor published in the fall of 2010 and was embraced as the first comprehensive reference to consider both fundamental and applied aspects of nanophysics. This follow-up project has been conceived as a necessary expansion and full update that considers the significant advances made in the field since 2010. It goes well beyond the physics as warranted by recent developments in the field. This seventh volume in a ten-volume set covers bioinspired systems and methods. Key Features: Provides the most comprehensive, up-to-date la...
Biomaterials are composed of metallic materials, ceramics, polymers, composites and hybrid materials. Biomaterials used in human beings require safety regulations, toxicity, allergic reaction, etc. When used as implantable materials their biological compatibility, biomechanical compatibility, and morphological compatibility must be acessed. This book explores the design and requirements of biomaterials for the use in implantology.