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Darwin's theory of evolution by natural selection was based on the observation that there is variation between individuals within the same species. This fundamental observation is a central concept in evolutionary biology. However, variation is only rarely treated directly. It has remained peripheral to the study of mechanisms of evolutionary change. The explosion of knowledge in genetics, developmental biology, and the ongoing synthesis of evolutionary and developmental biology has made it possible for us to study the factors that limit, enhance, or structure variation at the level of an animals' physical appearance and behavior. Knowledge of the significance of variability is crucial to th...
This volume considers the genetic variability of human populations, particularly in the tropics: its origins and maintenance, and its contribution to the phenotypic variability of complex characters. The first section deals with the ways of analysing genetic variation and provides a valuable review of relevant developments in molecular biology. The origin and maintenance of genetic diversity is considered in the second section with data presented for Pacific, African, Asian and Central American populations. The final section concerns characters in which the genetic contribution to variability is complex and shows how such characters may be used to elucidate biological problems of affinity and differentiation, of adaptation and survival. Published as part of the Decade of the Tropics research programme of the International Union of Biological Sciences, this volume will be of particular interest to human geneticists, physical and biological anthropologists.
Considers how the study of variation in plants has developed over the last 300 years.
Until about 10 years ago, the general view in the field was that Mycobacterium tuberculosis, the causative agent of human tuberculosis was a “clone” with insufficient natural sequence variation between clinical strains to be considered biologically and epidemiologically “relevant”. This view has now changed quite dramatically thanks to the –omics revolution, particularly the advent of next generation DNA sequencing. Large-scale comparative genomic studies over the last few years have revealed that M. tuberculosis clinical strains are more genetically diverse than appreciated previously. Moreover, an increasing number of experimental and epidemiological studies are showing that this...
Following a review of the diverse and scattered literature on gene flow and population differentiation, the author discusses the relationships among gene flow, dispersal, and migration. He then summarizes the factors which limit the geographic extent of gene flow, and those which allow steep clines to develop in the absence of barriers to gene flow. His analysis draws on examples from the field, experiments, and single- and multiple-locus models.
Biology For You has been updated to offer comprehensive coverage of the revised GCSE specifications. It can be used with either mixed ability or streamed sets and higher tier materials are clearly marked.
Biology as a subject not only plays a major role within the scientific world but has broader implications that cross many boundaries. This work takes a modern and innovative approach to teaching introductory biology; it presents fundamental biological concepts within the context of current social issues. How do scientists affect our society at large? How are ethics and morals applied to the scientific world? Why are we racing to complete the human genome project, and who are we racing against? How do economic disparities between people and nations influence habitat destruction? Can plant science feed the world? Are the causes of cancer more genetic or environmental? The book seeks to help students think critically about these questions and to explore and assess the role that science plays in their world.
"A subject collection from Cold Spring Harbor perspectives in medicine."