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Colorectal cancer remains to be a malignant and lethal disease with a poor survival rate and prognosis. The primary methods of treatment for patients with locally advanced rectal cancer (LARC), a combination of neoadjuvant chemoradiotherapy followed by total mesorectal excision is highly recommended. Neoadjuvant chemotherapy has been found to be significantly decrease local recurrence and make tumors more responsive to resection. However, the response can vary between patients and studies have highlighted approximately 15-40% of patients could obtain a pathological complete response (pCR) compared to 20% of patients who may show no side effects or symptoms following neoadjuvant chemotherapy.
La presente pubblicazione dedicata alla patologia non oncologica dell'Apparato Urogenitale nasce da un'idea del nucleo storico degli Uroradiologi italiani, in particolare del Prof. Antonio Rotondo, i quali si occupano da anni dell'argomento e che, sotto l'egida della Sezione di studio di radiologia urogenitale, hanno coinvolto autori, giovani e meno giovani, ma comunque rappresentativi degli addetti ai lavori, esperti di questa branca specialistica. Il testo intende fornire informazioni sullo stato dell'arte, che possano essere utili nella clinica, sia a chi pratica quotidianamente la disciplina sia a chi se ne occupa saltuariamente. L’opera è corredata da una ricca e significativa iconografia così come da schemi di semplificazione, che consentono di accedere rapidamente ai concetti fondamentali delle varie problematiche.
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In the elderly, the coexistence of various diseases, the presence of involutional and degenerative changes, and the occurrence of both physical and cognitive problems represent “the norm.” It is therefore important to know how to distinguish the healthy elderly from those in need of treatment as a sound basis for avoiding overdiagnosis and overtreatment. This aspect is a central theme in Geriatric Imaging, which covers a wide range of applications of different imaging techniques and clearly explains both the potential and the limitations of diagnostic imaging in geriatric patients. Individual sections are devoted to each major region or system of the body, and a concluding section focuses specifically on interventional procedures. The book, written by recognized experts in the field, is superbly illustrated and will be an ideal resource for geriatricians, radiologists, and trainees.
This book aims to provide a complete overview of the diagnosis and treatment of gastrointestinal stromal tumors (GISTs). It has been conceived to be both a detailed guide for clinical practice and an updated reference for all those involved in the evaluation of GISTs imaging. The publication provides comprehensive descriptions of the full range of common imaging and non imaging techniques used in the diagnosis and followup of GISTs. Techniques reviewed include: Conventional radiography· Endoscopy and endoscopic ultrasound· Conventional, color-Doppler and contrast-enhanced ultrasound· Computed tomography· Magnetic resonance imaging, and· Contrast-enhanced PET/CT imaging. Both medical and surgical treatment strategies are also fully reviewed. Finally, the book concludes with a chapter that aims to stimulate widespread interest in the formation of new GISTs Units. Written by experts in the field, the book is enriched throughout by numerous black-and-white and color images, making it an invaluable source of information as well as an indispensable guide to interpreting images for radiologists, gastroenterologists, pathologists, oncologists and surgeons.