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Statistical Methods for Survival Data Analysis
  • Language: en
  • Pages: 527

Statistical Methods for Survival Data Analysis

Third Edition brings the text up to date with new material and updated references. New content includes an introduction to left and interval censored data; the log-logistic distribution; estimation procedures for left and interval censored data; parametric methods iwth covariates; Cox's proportional hazards model (including stratification and time-dependent covariates); and multiple responses to the logistic regression model. Coverage of graphical methods has been deleted. Large data sets are provided on an FTP site for readers' convenience. Bibliographic remarks conclude each chapter.

Epigenetic Approaches in Drug Discovery, Development and Treatment
  • Language: en
  • Pages: 130

Epigenetic Approaches in Drug Discovery, Development and Treatment

Establishment of a normal phenotype involves dynamic epigenetic regulation of gene expression that when affected contributes to human diseases. On a molecular level, epigenetic regulation is marked by specific covalent modifications (acetylation, methylation, phosphorylation, sumoylation, PARylation and ubiquitylation) of DNA and its associated histones. Studies also suggest the influence of such epigenetic modifications on non-coding RNA expression implicated in normal and diseased phenotypes. Epigenetic control of genetic expression is a reversible process essential for normal development and function of an organism. Alteration of epigenetic regulation leads to various disease forms such a...

Functional screening for cancer drug discovery: From experimental approaches to data integration
  • Language: en
  • Pages: 136
Algorithms and Architectures for Parallel Processing
  • Language: en
  • Pages: 375

Algorithms and Architectures for Parallel Processing

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Records of Han Dynasty
  • Language: en

Records of Han Dynasty

  • Type: Book
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  • Published: Unknown
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  • Publisher: DeepLogic

Zi Zhi Tong Jian (Chinese: 资治通鉴;English: "Comprehensive Mirror in Aid of Governance") is a pioneering reference work in Chinese historiography, published in 1084 in the form of a chronicle. In 1065 AD, Emperor Yingzong of Songordered the great historian Sima Guang (1019–1086 AD) to lead with other scholars such as his chief assistants Liu Shu, Liu Ban and Fan Zuyu,[1] the compilation of a universal history of China. The task took 19 years to be completed,and, in 1084 AD, it was presented to his successor Emperor Shenzong of Song. The Zizhi Tongjian records Chinese history from 403 BC to 959 AD, covering 16 dynasties and spanning across almost 1,400 years,and contains 294 volumes (...

Optimization of Complex Systems: Theory, Models, Algorithms and Applications
  • Language: en
  • Pages: 1164

Optimization of Complex Systems: Theory, Models, Algorithms and Applications

  • Type: Book
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  • Published: 2019-06-15
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  • Publisher: Springer

This book contains 112 papers selected from about 250 submissions to the 6th World Congress on Global Optimization (WCGO 2019) which takes place on July 8–10, 2019 at University of Lorraine, Metz, France. The book covers both theoretical and algorithmic aspects of Nonconvex Optimization, as well as its applications to modeling and solving decision problems in various domains. It is composed of 10 parts, each of them deals with either the theory and/or methods in a branch of optimization such as Continuous optimization, DC Programming and DCA, Discrete optimization & Network optimization, Multiobjective programming, Optimization under uncertainty, or models and optimization methods in a specific application area including Data science, Economics & Finance, Energy & Water management, Engineering systems, Transportation, Logistics, Resource allocation & Production management. The researchers and practitioners working in Nonconvex Optimization and several application areas can find here many inspiring ideas and useful tools & techniques for their works.

The Military History in Qin and Han Dynasty
  • Language: en

The Military History in Qin and Han Dynasty

  • Type: Book
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  • Published: Unknown
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  • Publisher: DeepLogic

The book is the volume of “The Military History in Qin and Han Dynasty” among a series of books of “Deep into China Histories”. The earliest known written records of the history of China date from as early as 1250 BC, from the Shang dynasty (c. 1600–1046 BC) and the Bamboo Annals (296 BC) describe a Xia dynasty (c. 2070–1600 BC) before the Shang, but no writing is known from the period The Shang ruled in the Yellow River valley, which is commonly held to be the cradle of Chinese civilization. However, Neolithic civilizations originated at various cultural centers along both the Yellow River and Yangtze River. These Yellow River and Yangtze civilizations arose millennia before the...

Staging Tianxia
  • Language: en
  • Pages: 260

Staging Tianxia

  • Categories: Art

Staging Tianxia explores the ancient Chinese vision of world order known as tianxia (all under heaven) by focusing on the historical, performative, and rhetorical processes of expressive arts and cultural heritages that inform a vision of China as a historically multiethnic and cosmopolitan nation. Author Lanlan Kuang unites multimedia ethnographic research and theoretical insights from ethnomusicology, philosophy, religious studies, performance studies, and cognitive science, with a focus on Dunhuang bihua yuewu, a modern interpretation inserted into the Chinese classical dance and theatrical arts tradition. Staging Tianxia thus aims to redefine Silk Road studies and Dunhuangology, a transdisciplinary field dedicated to studying the texts and art of Dunhuang, a UNESCO World Heritage Site that connected China via the Silk Road with Central Asia, South Asia, Europe, and the Middle East. Staging Tianxia is a careful ethnographic study that looks at the importance of performance tradition and poetics in the arts and aesthetic theory of China.

Book of Wei Dynasty (Volume II)
  • Language: en

Book of Wei Dynasty (Volume II)

  • Type: Book
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  • Published: Unknown
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  • Publisher: DeepLogic

The Twenty-Four Histories (Chinese: 二十四史) are the Chinese official historical books covering a period from 3000 BC to the Ming dynasty in the 17th century. The Han dynasty official Sima Qian established many of the conventions of the genre. Starting with the Tang dynasty, each dynasty established an official office to write the history of its predecessor using official court records. As fixed and edited in the Qing dynasty, the whole set contains 3213 volumes and about 40 million words. It is considered one of the most important sources on Chinese history and culture. The title "Twenty-Four Histories" dates from 1775 which was the 40th year in the reign of the Qianlong Emperor. This ...

Political History of the Ming Dynasty
  • Language: en

Political History of the Ming Dynasty

  • Type: Book
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  • Published: Unknown
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  • Publisher: DeepLogic

The book is the volume of “Political History of the Ming Dynasty” among a series of books of “Deep into China Histories”. The earliest known written records of the history of China date from as early as 1250 BC, from the Shang dynasty (c. 1600–1046 BC) and the Bamboo Annals (296 BC) describe a Xia dynasty (c. 2070–1600 BC) before the Shang, but no writing is known from the period The Shang ruled in the Yellow River valley, which is commonly held to be the cradle of Chinese civilization. However, Neolithic civilizations originated at various cultural centers along both the Yellow River and Yangtze River. These Yellow River and Yangtze civilizations arose millennia before the Shang...