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Brain Tumor Immunotherapy
An authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and related strategies, and include many vanguard experimental strategies and immunological techniques for studying brain tumor immunotherapy. Cutting-edge and comprehensive, Brain Tumor Immunotherapy brings together all the important recent advances in our understanding of central nervous system tumor immunology and illustrates in powerful detail the many new applications now harnessing the immune response for brain tumor therapeutics.
TRAIL
The discovery of TRAIL (TNF Related Apoptosis Inducing Ligand), also referred to as Apo-2, is in an era of intense research because TRAIL induces many cancer cells to undergo programmed cell death (apoptosis), while having no effect on normal cells. This important protein deserves extensive review at a formative time in the devlopement of our knowledge concerning its mechanism of action and the ways in which it can be used as a cancer chemotherapeutic agent. Consequently, this voume reviews the current status of research on TRAIL. Selected Contents:* Crystal Structure of RANK Ligand involved in bone metabolism* Promoter of TRAIL-R2 Gene* Monoclonal Antibodies against TRAIL* Modulation of TRAIL signaling complex* TRAIL in the airways* FLIP Protein and TRAIL-Induced Apoptosis* TRAIL and Ceramide* TRAIL and Viral Infection* TRAIL and Malignant Glioma
Uniting Europe
This book sets out to give a straightforward insider''s account of the current realities of European integration. It succinctly reviews the reasons and methods of European integration, analyses what the European Union (EU) really does, and examines how funds are spent. The whole range of current EU policies is critically reviewed: the Single market; the Euro; and the common policies on agriculture, fisheries, the regions, industry, competition, transport, the environment, social affairs, consumer protection, research, taxation, justice, trade, development, foreign affairs and defence.This book argues for a much slimmed-down European executive. It needs to become fully accountable in a democr...
Colorectal Cancer Liver Metastases
Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the lat...
Roth Time
Sculptor, poet, diarist, graphic designer, pioneer artist's book maker, performer, publisher, musician, and, most of all, provocateur, Dieter Roth has long been beloved as an artist's artist. Known for his mistrust of all art institutions and commercial galleries--he once referred to museums as funeral homes--he was also known for his generosity to friends, his collaborative spirit, and for including his family in his art making. Much to the frustration of any gallery that tried to exhibit his work (supposedly none more than once), Roth thumbed his nose at those who valued high purpose and permanence in art. Constantly trying to undo his art education, he would set up systems that discourage...
AACR 2019 Proceedings: Abstracts 2749-5314
American Association for Cancer Research 2019 Proceedings: Abstracts 2749-5314 - Part B
