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Interleukin 12: Antitumor Activity and Immunotherapeutic Potential in Oncology
  • Language: en
  • Pages: 80

Interleukin 12: Antitumor Activity and Immunotherapeutic Potential in Oncology

  • Type: Book
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  • Published: 2016-09-23
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  • Publisher: Springer

This book discusses the immunotherapeutic potential of Interleukin 12 in the context of clinical oncology, as well as antitumor effects confirmed in preclinical studies and clinical trials in cancer immunotherapy. Due to its ability to activate both innate (NK cells) and adaptive (cytotoxic T lymphocytes) immunities, Interleukin 12 (IL-12) has been regarded as a promising candidate for tumor immunotherapy. However, despite the encouraging results in animal models, only very modest antitumor effects have been confirmed in early clinical trials. Recently, several clinical studies have been initiated in which IL-12 was applied as an adjuvant in cancer vaccines, in gene therapy including locoregional injections of IL-12 plasmid, and in the form of tumor-targeting immunocytokines (IL-12 fused to monoclonal antibodies).

Immunologia
  • Language: pl

Immunologia

  • Type: Book
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  • Published: 2023
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  • Publisher: Unknown

None

Immunologia
  • Language: pl
  • Pages: 498

Immunologia

  • Type: Book
  • -
  • Published: 2017
  • -
  • Publisher: Unknown

None

Journal of Clinical & Laboratory Immunology
  • Language: en
  • Pages: 496

Journal of Clinical & Laboratory Immunology

  • Type: Book
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  • Published: 1986
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  • Publisher: Unknown

None

Cancer Immunology, Immunotherapy
  • Language: en
  • Pages: 470

Cancer Immunology, Immunotherapy

  • Type: Book
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  • Published: 1995
  • -
  • Publisher: Unknown

None

Folia haematologica
  • Language: en
  • Pages: 1038

Folia haematologica

  • Type: Book
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  • Published: 1985
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  • Publisher: Unknown

Supplements accompany some numbers.

Immunologia
  • Language: pl
  • Pages: 193

Immunologia

  • Type: Book
  • -
  • Published: 2000
  • -
  • Publisher: Unknown

None

Acta Biochimica Polonica
  • Language: en
  • Pages: 510

Acta Biochimica Polonica

  • Type: Book
  • -
  • Published: 2007
  • -
  • Publisher: Unknown

None

Anticancer Research
  • Language: en
  • Pages: 1006

Anticancer Research

  • Type: Book
  • -
  • Published: 1997
  • -
  • Publisher: Unknown

None

Zeitschrift Für Naturforschung
  • Language: en
  • Pages: 362

Zeitschrift Für Naturforschung

  • Type: Book
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  • Published: 2005
  • -
  • Publisher: Unknown

None