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Mechanisms Underlying Host-Microbiome Interactions in Pathophysiology of Human Diseases
Only recently have we begun to appreciate the role of microbiome in health and disease. Environmental factors and change of life style including diet significantly shape human microbiome that in turn appears to modify gut barrier function affecting nutrient & electrolyte absorption and inflammation. Approaches that can reverse the gut dysbiosis represent as reasonable and novel strategies for restoring the balance between host and microbes. In the book, we offer summary and discussion on the advances in understanding of pathophysiological mechanisms of microbial host interactions in human diseases. We will not only discuss intestinal bacterial community, but also viruses, fungi and oral microbiome. Microbiome studies will facilitate diagnosis, functional studies, drug development and personalized medicine. Thus, this book will further highlight the microbiome in the context of health and disease, focusing on mechanistic concepts that underlie the complex relationships between host and microbes.
Genetics and Epigenetics of Psychiatric Diseases, 2nd Edition
Psychiatric diseases have a highly complex etiology, aggregating in families but not segregating in a traditional Mendelian manner. Recent approaches to understanding the causes of psychiatric disease have focused on describing the genetic contribution to major psychiatric illnesses; the use of large-scale genome-wide association studies (GWAS) and exome sequencing has enabled a systematic exploration of genetic risk factors and identified over 100 independent genomic loci significantly associated with psychiatric diseases; however, there remains uncertainty about the causal genes involved in disease pathogenesis, and how their function is regulated. Since many GWAS variants reside in non-co...
Outlaws of the Sea
In Outlaws of the Sea, Robert J. Antony provides a comprehensive account of the history of maritime piracy in coastal south China from the 1630s to the 1940s. He neither romanticizes nor maligns pirates, but rather analyzes them in the context of their times and the broader world in which they lived. The author demonstrates that Chinese piracy was a pervasive force shaping maritime society as it ebbed and flowed between sporadic, small-scale ventures and professional, large-scale enterprises in the modern era. This book offers important new insights into the underside of modern China’s history and the interactions between pirates, foreign traders, local communities, and the state. “How c...
AACR 2016: Abstracts 1-2696
The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 1-2696 presented on April 17-18, 2016, at the AACR Annual Meeting.
Passion On Beauty Rather Than Power
In that life, after the war had set the Three Realms on fire, the youth had embraced the girl and covered her with his arms.In the previous period of time, the Immortal Lord suffered a setback from the Heavenly Tribulation. The woman took care of the Immortal Lord who returned to his original body carefully, while the Immortal Lord continued to cry and sigh every day.At this moment, under the Hibiscus tree in full bloom, the youth had a dazzling smile. He decided that he would not let go of it again.No matter how many reincarnations I pass through, I will still be me, and you will still be you.
Daily Report
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Daily Report
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Subaltern China
Behind China’s growing economic and political power is a vast underworld of marginalized social groups. In this powerful and timely book, Wanning Sun focuses on the country’s hundreds of millions of rural migrant workers, who embody China's most intractable problems of inequality. Drawing on rich and extensive fieldwork, the author argues that despite the critical role their labor has played in enabling and sustaining the country’s remarkable economic growth, workers and peasants have become the nation’s “subalterns.” Sun focuses especially on the role of media and culture in negotiating the unequal relationships that exist between various social groups. She shows that in the fac...
