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Immune Regulations of Inflammatory Skin Diseases
Skin is our primary interface with the environment, and T cells are crucial for orchestrating host immune responses against pathogenic microorganisms. Dysregulated immune responses, on the other hand, can result in chronic inflammatory skin diseases. The complex regulatory networks include effector T cells, memory T cells, regulatory T cells, immunoregulatory co-signaling molecules and cytokines that control skin immunity, and the mechanisms that regulate skin immune responses in host defense and in immune-mediated cutaneous diseases. The immune-regulatory networks are involved in the common inflammatory skin diseases, including psoriasis, atopic dermatitis, alopecia areata, vitiligo, bullous diseases, and cutaneous adverse drug reaction. The goal of this Research Topic is to provide a forum to advance research on the contribution of skin inflammation to the genesis and development of the skin diseases as well as to explore innovative skin-oriented pharmacological interventions, mainly on the immune regulatory networks, in the attempt to achieve a beneficial impact on the skin disease course.
Metacinema in Contemporary Chinese Film
Depictions within a movie of either filmmaking or film watching are hardly novel, but the dramatic expansion of the reach of the metacinematic into contemporary Chinese cinemas is nothing short of remarkable. To G. Andrew Stuckey, the prevalence of metacinematic features forms the basis of a discourse on film arising from the films themselves. Such a discourse, in turn, outlines the boundaries of the possible for film in China as aesthetic or sociopolitical practice. Metacinema also draws our attention to the presence of the audience, people actively responding to a film. In elucidating the affective responses elicited by the metacinematic mode in the viewers, Stuckey argues that metacinema ...
Miss Su, I Write Poems For You
Su Jingen had three good points. Her delicate body was easy to push down. In front of humans, she was a harmless little lamb, yet after humans, she transformed into a big grey wolf.The schemes and tricks were all accepted, and the grudge would be repaid in double.But who would have thought that the big bad wolf would run into Wang Zhong Wang.The thing she regretted the most was climbing into Wei Jinghan's car and biting the person who kissed him on the neck.He watched on helplessly as Wei Jinghan dug a hole for him to jump into step by step. He had no place to escape.
Limited Views
This translation of 65 pieces from Qian Zhongshu's Guanzhui bian (Limited Views) makes available for the first time in English a representative selection from Qian's massive four-volume collection of essays and reading notes on the classics of early Chinese literature.
Ex-husband Spoils His Wife Without Limit
He was the tyrant of A City's shopping mall, but he was also her brother-in-law. However, an accident had brought them into a marriage.He had thought that he would be able to win her love with just a little effort, but he had actually sent her to the operating table to cut her heart out.She had managed to escape death and did not want to get entangled with him anymore. However, the truth was revealed, and he continued to pursue her relentlessly."Song Wanqing, in this life, you will be my man, and death will be my ghost. Don't even think about escaping.""Young Master Fu, just give it a try."
From the Khitans to the Jurchens & Mongols
From the Khitans to the Jurchens & Mongols, A History of Barbarians in Triangle Wars & Quartet Conflicts is the third book of The Scourge of God Tetralogy. This is a book with comprehensive writeup of the barbarians’ history spanning more than one thousand years, from before the anno domini eras and inclusive of the expulsion of the Mongols from China. The subtitle about the barbarians in triangle wars & quartet conflicts is self-explanatory for the historical environment of different groups of barbarians successively rising up on the steppes to overpower the former with more savagery. This third book, while carrying a title with emphasis on the Khitans, the Jurchens and Mongols, also cove...
International Conference on Biomedical and Health Informatics
This volume presents the proceedings of the International Conference on Biomedical and Health Informatics (ICBHI). The conference was a new special topic conference and a common initiative by the International Federation of Medical and Biological Engineering (IFMBE) and IEEE Engineering in Medicine and Biology Society (IEEE- EMBS). BHI2015 was held in Haikou, China, 8-10 October 2015. The main theme of the BHI2015 is “The Convergence: Integrating Information and Communication Technologies with Biomedicine for Global Health”. The ICBHI2015 proceedings examine enabling technologies of sensors, devices and systems that optimize the acquisition, transmission, processing, storage, retrieval, use of biomedical and health information as well as to report novel clinical applications of health information systems and the deployment of m-Health, e-Health, u-Health, p-Health and Telemedicine.
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Tumor Microenvironment and Cancer Therapy
It is well established that the tumor microenvironment(TME) plays a pivotal role in tumor initiation, progression and therapeutic resistance by creating a dynamic interaction with cancer cells. TME is comprised of extracellular matrix (ECM), growth factors, nutrients, blood and lymphatic vessels, and non-cancer stromal cells, which serve as a sustained niche for cancer cells to proliferate and metastasize. Notably, various cellular components in TME, including endothelial cells, fibroblasts, pericytes, adipocytes, immune cells, cancer stem cells, and vasculature, could promote tumor’s immune evasion and growth.
