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The Influence of Global Environmental Change on Infectious Disease Dynamics
The twentieth century witnessed an era of unprecedented, large-scale, anthropogenic changes to the natural environment. Understanding how environmental factors directly and indirectly affect the emergence and spread of infectious disease has assumed global importance for life on this planet. While the causal links between environmental change and disease emergence are complex, progress in understanding these links, as well as how their impacts may vary across space and time, will require transdisciplinary, transnational, collaborative research. This research may draw upon the expertise, tools, and approaches from a variety of disciplines. Such research may inform improvements in global readi...
A Research Review of Interventions to Increase the Persistence and Resilience of Coral Reefs
Coral reef declines have been recorded for all major tropical ocean basins since the 1980s, averaging approximately 30-50% reductions in reef cover globally. These losses are a result of numerous problems, including habitat destruction, pollution, overfishing, disease, and climate change. Greenhouse gas emissions and the associated increases in ocean temperature and carbon dioxide (CO2) concentrations have been implicated in increased reports of coral bleaching, disease outbreaks, and ocean acidification (OA). For the hundreds of millions of people who depend on reefs for food or livelihoods, the thousands of communities that depend on reefs for wave protection, the people whose cultural pra...
Preparation of Phytopharmaceuticals for the Management of Disorders
Preparation of Phytopharmaceuticals for the Management of Disorders: The Development of Nutraceuticals and Traditional Medicine presents comprehensive coverage and recent advances surrounding phytopharmaceuticals, nutraceuticals and traditional and alternative systems of medicines. Sections cover the concepts of phytopharmaceuticals, their history, and current highlights in phytomedicine. Also included are classifications of crude drugs, herbal remedies and toxicity, traditional and alternative systems of medicine, nanotechnology applications, and herbal cosmeticology. Final sections cover applications of microbiology and biotechnology in drug discovery. This book provides key information fo...
Carbohydrate Mimics
Carbohydrate Mimics Concepts and Methods Edited by Yves Chapleur Apart from the various functions of carbohydrates in natural processes they are important building blocks for drugs, especially antibiotics. In addition, carbohydrates are considered as important structures in the immunological recognition process of the antigen-antibody reaction. The modification of the structure and thereby the chemistry of substrates is a common procedure in nature. This naturally occurring process is reflected in the concept of molecular mimicry, which has become a useful approach in drug discovery. The search for carbohydrate analogues that exhibit better binding activity, biological activity, and stabilit...
Antibiotic Discovery and Development
This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
Primates in Fragments
This book is number two in a series for Primates in Fragments. In this volume, ten years after the first http://www.springer.com/social+sciences/anthropology+%26+archaeology/book/978-0-306-47696-9, we continue to address issues regarding primates within a fractured landscape. There are seven sections based on specific categories of primates in fragments. In the Introductory section, authors discuss the issues surrounding primates in remnant habitats as well as encourage discussion about what we mean by fragmentation on a landscape scale. In the Long-Term and Regional Studies section, authors present information on changes that have occurred during longer studies as well as changes that have ...
From Protein Structure to Function with Bioinformatics
Proteins lie at the heart of almost all biological processes and have an incredibly wide range of activities. Central to the function of all proteins is their ability to adopt, stably or sometimes transiently, structures that allow for interaction with other molecules. An understanding of the structure of a protein can therefore lead us to a much improved picture of its molecular function. This realisation has been a prime motivation of recent Structural Genomics projects, involving large-scale experimental determination of protein structures, often those of proteins about which little is known of function. These initiatives have, in turn, stimulated the massive development of novel methods ...
Bioreactors for Microbial Biomass and Energy Conversion
This book discusses recent trends and developments in the microbial conversion process, which serves as an important route for biofuel production, with particular attention to bioreactors. It combines microbial conversion with multiphase flow and mass transfer, providing an alternative perspective for the understanding of microbial biomass and energy production process as well as enhancement strategy. This book is relevant to students and researchers who work in the fields of renewable energy, engineering and biotechnology. Policymakers, economists and industry engineers also benefit from this book, as it can be used as a resource for the implementation of renewable energy technologies.
The Fungal Community
The Fungal Community: Its Organization and Role in the Ecosystem, Third Edition addresses many of the questions related to the observations, characterizations, and functional attributes of fungal assemblages and their interaction with the environment and other organisms. This edition promotes awareness of the functional methods of classification over taxonomic methods, and approaches the concept of fungal communities from an ecological perspective, rather than from a fungicentric view. It has expanded to examine issues of global and local biodiversity, the problems associated with exotic species, and the debate concerning diversity and function. The third edition also focuses on current ecol...
Ophthalmic Anaesthesia
This Oxford Specialist Handbook is a concise, practical yet comprehensive guide to ophthalmic anaesthesia, covering anatomy, specific anaesthetic techniques and principles, and recent changes in the field.
