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The Baker and the Blacksmith
It’s 1902 and Daniel has left a life of luxury in New York to run his late uncle’s bakery in Milford, Pennsylvania. Though he’s made many friends in the small town, not everything has been rosy. His uncle’s outstanding loan has fallen upon his shoulders and he could lose the bakery if he doesn’t pay it back in time. Additionally, Daniel feels that lecherous loan officer Simon Prickson is actively trying to make it harder for him to repay his debt. Furthermore, not everyone in Milford likes him. Adrian Dane, the cantankerous town blacksmith, seems to hate Daniel, and he has no idea why. Though Daniel finds Adrian irritating in every way, the two can’t manage to stay away from each other. Will Daniel ever figure out what he’s done to upset the inscrutable man? Can either find the companion they so desperately need?
The Functional Nucleus
This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.
Honeysuckle Love
Andreas Keller is a certified trainwreck. He’s young, emancipated, broke, and has a budding criminal record. When a judge mercifully sentences him to community service instead of jail time, Keller is faced with the most horrible thing he can imagine -- three hundred hours of mandatory volunteer work with the minister's son. Cameron’s job at the library is interrupted when he’s assigned to supervise the town troublemaker. He has no idea what to expect when he begins working with Keller, but it certainly isn’t friendship. Is there more to Keller than meets the eye? Can the two overcome their differences and past trauma? Or will a horrible bet ruin everything between them?
Biomedical Photonics Handbook
A wide variety of biomedical photonic technologies have been developed recently for clinical monitoring of early disease states; molecular diagnostics and imaging of physiological parameters; molecular and genetic biomarkers; and detection of the presence of pathological organisms or biochemical species of clinical importance. However, available information on this rapidly growing field is fragmented among a variety of journals and specialized books. Now researchers and medical practitioners have an authoritative and comprehensive source for the latest research and applications in biomedical photonics. Over 150 leading scientists, engineers, and physicians discuss state-of-the-art instrumentation, methods, and protocols in the Biomedical Photonics Handbook. Editor-in-Chief Tuan Vo-Dinh and an advisory board of distinguished scientists and medical experts ensure that each of the 65 chapters represents the latest and most accurate information currently available.
Chromatography of Antibiotics
Chromatography of Antibiotics
Genetic Engineering of Microorganisms for Chemicals
The normal course of most biologically catalyzed processes is tightly regulated at the genetic and physiological levels. The regulatory mechanisms are diverse, sometimes redundant, and it is becoming increasingly apparent that, at the genetic level, the range of mechanisms may be limited only by the permutations and combina tions available. For each microbial cell, evolution appears to have resulted in maximized advantage to that cell, achieving regulatory balance. Genetic engineering encompasses our attempts to perturb the genetic regulation of a cell so that we may obtain desired other than normal outcomes, such as increased product formation, or new product formation. Following the ground...
Phoning It In
To the public, Harper Miller is nothing more than a mild mannered, socially awkward English professor with a slight stutter and some control issues. She knows her public persona isn’t glamorous, but she doesn’t care if people see her as milquetoast. She prefers it that way because it means no one would ever suspect her secret. Harper never intended to run a phone sex line long term. It was meant to help her pay off her student loans before landing a job with a decent paycheck. Of course, Harper never intended to fall for a client either. After talking to a caller that goes by Em for six months, Harper can admit she’s thoroughly smitten, even though her mystery woman may not be who she seems. What happens when Em’s true identity is discovered? Will Harper be able to look past old grievances for a shot at true love?
Telomeres and Telomerase in Cancer
Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved in cancer biology, and as promising diagnostic tools and therapeutic targets. Recently, role of telomerase in “cancer stem cells” has become another attractive story. Until now, there are several good books on telomere and telomerase focusing on biology in ciliates, yeasts, and mouse or basic sciences in human, providing basic scientists or students with updated knowledge.
Transitions Towards Sustainable Mobility
Delivering a sustainable transport system is not just a matter of adopting a number of technological innovations to improve performance in terms of people, planet, and profits. A broader structural and societal transition is needed in technology, as well as in institutions, behavioural patterns, and the economy as a whole. In this broader view, neither the free market nor the public sector will be the unique key player in making this transition happen. Elements of such an approach are presented in this book in a number of domains: integrating transport infrastructure and land use planning, thus connecting fields that are rather unconnected in day-to-day policies; experiments with dynamic transport optimization, including reports on pilot projects to test the viability of transitions; towards reliable transport systems, describing a reversal from supply-driven towards demand-driven approaches; and sustainable logistics and traffic management, from ‘local’ city distribution to global closed supply chain loops.
Chromatography of Antibiotics
Chromatography of Antibiotics
