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The Calculus of Life
  • Language: en
  • Pages: 100

The Calculus of Life

  • Type: Book
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  • Published: 2015-04-13
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  • Publisher: Springer

This book explores the exciting world of theoretical biology and is divided into three sections. The first section examines the roles played by renowned scientists such as Jacob, Monod, Rosen, Turing, von Bertalanffy, Waddington and Woodger in developing the field of theoretical biology. The second section, aided with numerous examples, supports the idea that logic and computing are suitable formal languages to describe and understand biological phenomena. The third and final section is, without doubt, the most intellectually challenging and endeavors to show the possible paths we could take to compute a cell - the basic unit of life - or the conditions required for a predictive theory of biological evolution; ultimately, a theory of life in the light of modern Systems Biology. The work aims to show that modern biology is closer than ever to making Goethe's dream come true and that we have reached a point where synthetic and analytical traditions converge to shed light on the living being as a whole.

Between Pathogenicity and Commensalism
  • Language: en
  • Pages: 360

Between Pathogenicity and Commensalism

This comprehensive, interdisciplinary book covers different aspects of relevant human pathogens and commensals. The ongoing development of (meta-)genomic, transcriptomic, proteomic and bioinformatic analyses of pathogenic and commensal microorganisms and their host interaction provides a comprehensive introduction to the microbiological analysis of host-microbe interplay and its consequences for infection or commensalism.

Structural Approaches to Sequence Evolution
  • Language: en
  • Pages: 375

Structural Approaches to Sequence Evolution

Recent advances in understanding the thermodynamics of macromolecules, the topological properties of gene networks, the organization and mutation capabilities of genomes, and the structure of populations make it possible to incorporate these key elements into a broader and deeply interdisciplinary view of molecular evolution. This book gives an account of such a new approach, through clear tutorial contributions by leading scientists.

(Endo)symbiotic Methanogenic Archaea
  • Language: en
  • Pages: 245

(Endo)symbiotic Methanogenic Archaea

This updated monograph deals with methanogenic endosymbionts of anaerobic protists, in particular ciliates and termite flagellates, and with methanogens in the gastrointestinal tracts of vertebrates and arthropods. Further chapters discuss the genomic consequences of living together in symbiotic associations, the role of methanogens in syntrophic degradation, and the function and evolution of hydrogenosomes, hydrogen-producing organelles of certain anaerobic protists. Methanogens are prokaryotic microorganisms that produce methane as an end-product of a complex biochemical pathway. They are strictly anaerobic archaea and occupy a wide variety of anoxic environments. Methanogens also thrive in the cytoplasm of anaerobic unicellular eukaryotes and in the gastrointestinal tracts of animals and humans. The symbiotic methanogens in the gastrointestinal tracts of ruminants and other “methanogenic” mammals contribute significantly to the global methane budget; especially the rumen hosts an impressive diversity of methanogens. This makes this updated volume an interesting read for scientists and students in Microbiology and Physiology.

Synthetic Biology engineering complexity and refactoring cell capabilities
  • Language: en
  • Pages: 125

Synthetic Biology engineering complexity and refactoring cell capabilities

One of the key features of biological systems is complexity, where the behavior of high level structures is more than the sum of the direct interactions between single components. Synthetic Biologists aim to use rational design to build new systems that do not already exist in nature and that exhibit useful biological functions with different levels of complexity. One such case is metabolic engineering, where, with the advent of genetic and protein engineering, by supplying cells with chemically synthesized non-natural amino acids and sugars as new building blocks, it is now becoming feasible to introduce novel physical and chemical functions and properties into biological entities. The rule...

Life Out of the Shadows
  • Language: en

Life Out of the Shadows

  • Type: Book
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  • Published: 2022
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  • Publisher: Unknown

This paper examines the effects of a government regularization program offered to half a million Venezuelan refugees in Colombia. For this purpose, 2,232 surveys of refugee families were collected and used to compare refugees who arrived in Colombia around a specified eligibility date in 2018. The analysis finds that program beneficiaries experienced improvements in consumption (60 percent), income (31 percent), physical and mental health (1.8 sd), registration rates in the system that assesses vulnerability and awards public transfers (40 pp), and financial services (64.3 pp), relative to other refugees. The program also induced a change in labor formalization of 10 pp.

The Behavioral Consequences of Violence
  • Language: en

The Behavioral Consequences of Violence

  • Type: Book
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  • Published: 2013
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  • Publisher: Unknown

Shocks and traumatic experiences can alter the way in which individuals behave and deplete their ability to make economic decisions. In this dissertation, I analyze how risk attitudes, hope, and expectations, which are central components of the economic decision-making process, change after the direct experience violence. I also provide psychological evidence that explains why these dimensions of behavior change. For this purpose, I bring together micro-level data from a living standards survey, a questionnaire on household victimization, and a psychological stress scale, with data from economic experiments designed to measure risk attitudes, hope, and expectations of future household mobili...

Colloquium on Variation and Evolution in Plants and Microorganisms--Toward a New Synthesis--50 Years After Stebbins
  • Language: en
  • Pages: 361

Colloquium on Variation and Evolution in Plants and Microorganisms--Toward a New Synthesis--50 Years After Stebbins

Annotation In 1950, Stebbins (d. 2000) published Variation and Evolution in Plants, which extended the synthetic theory of evolution or "the modern synthesis" to plants. These 17 papers are drawn from a National Academy of Sciences colloquium held in January 2000 on the 50th anniversary of the publication of Stebbins' classic. Following a Stebbins appreciation talk (originally slotted for his own words), papers branch into sections on: early evolution and the origin of cells, virus and bacterial models, protoctist models (having to do with RNA editing), population variation, and trends and patterns in plant evolution. Annotation c. Book News, Inc., Portland, OR (booknews.com).

Life as We Know It
  • Language: en
  • Pages: 714

Life as We Know It

Life As we Know It covers several aspects of Life, ranging from the prebiotic level, origin of life, evolution of prokaryotes to eukaryotes and finally to various affairs of human beings. Although Life is hard to define, one can characterize it and describe its features. The information presented here on the various phenomena of Life were all written by highly qualified authors including scientists, a professional athlete and three Nobel Laureates.

Evolution from the Galapagos
  • Language: en
  • Pages: 177

Evolution from the Galapagos

This volume is a collection of the some of the most significant lectures that well-known experts presented at our two international “summits on evolution” (2005, 2009) as updated and revised chapters. The meetings took place on one of the large islands of the Galapagos archipelago (San Cristobal) at GAIAS (Galapagos Institute for the Arts and Sciences) of the Universidad San Francisco de Quito (USFQ), Ecuador.​ The main goal of the two Galapagos Summits on Evolution has been to bring together scientists and graduate students engaged in the study of evolution, from life’s origin to its current diversity. Because of their historical significance, the Galapagos are a unique venue for promoting comprehensive research on evolution and ecology and to make the research results available to students and teachers everywhere, but especially from developing countries. As shown by the enthusiastic attendance at both summits and the many suggestions to keep them continuing, the meetings have opened new opportunities for students from Ecuador and other Latin American countries to be inspired by some of the most brilliant minds in evolutionary science.