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Semaphorin 3F Modulates Corneal Lymphangiogenesis and Promotes Corneal Graft Survival
Abstract: Purpose: Corneal vascularization significantly increases the risk for graft rejection after keratoplasty. Semaphorin 3F (Sema3F) is a known modulator of physiologic avascularity in the outer retina. The aim of this study was to investigate whether Sema3F is involved in maintaining corneal avascularity and can reduce the risk for corneal graft rejection. Methods: Corneal Sema3F expression was investigated using immunohistochemistry and qPCR in human and murine tissue. Pathologic invasion of blood and lymph vessels into corneal tissue was analyzed in the murine corneal suture and high-risk keratoplasty model. The anti-lymphangiogenic effects of Sema3F were further investigated using ...
Jo Anne Schneider
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Schneider, Anne
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OECD Regional Development Studies Working Together for Local Integration of Migrants and Refugees
This report describes what it takes to formulate a place-based approach to migrant integration, drawing on both quantitative evidence, from a statistical database, and qualitative evidence, from a survey of European 72 cities and 10 case studies.
OECD Regional Development Studies Working Together for Local Integration of Migrants and Refugees in Paris
Of the requests for asylum in France made in 2016, more than 10 000 applications were made by people in Paris and were made in the context of a rising number of refugees and asylum seekers since 2015. This increase has stirred a debate in France around its “universal” migrant integration model ...
Callander Square
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An Introduction to German Pietism
An up-to-date portrait of a defining moment in the Christian story—its beginnings, worldview, and cultural significance. Winner of the Dale W. Brown Book Award of the Young Center for Anabaptists and Pietist Studies at Elizabethtown College An Introduction to German Pietism provides a scholarly investigation of a movement that changed the history of Protestantism. The Pietists can be credited with inspiring both Evangelicalism and modern individualism. Taking into account new discoveries in the field, Douglas H. Shantz focuses on features of Pietism that made it religiously and culturally significant. He discusses the social and religious roots of Pietism in earlier German Radicalism and s...
