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Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 12
Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable re...
Immunopsychiatry
This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice.
Anthropological Perspectives on Aging
An in-depth and wide-ranging approach to the study of older adults in society Taking a holistic approach to the study of aging, this volume uses biological, archaeological, medical, and cultural perspectives to explore how older adults have functioned in societies around the globe and throughout human history. As the world’s population over 65 years of age continues to increase, this wide-ranging approach fills a growing need for both academics and service professionals in gerontology, geriatrics, and related fields. Case studies from the United States, Tibet, Turkey, China, Nigeria, and Mexico provide examples of the ways age-related changes are influenced by environmental, genetic, socio...
Lipopolysaccharides (LPSs)
The cytoplasm of Gram-negative bacteria is bound by three layers: an inner membrane, a layer of peptidoglycan, and an outer membrane. The outer membrane is an asymmetric lipidic bilayer, with phospholipids on its inner surface and lipopolysaccharides (LPSs) on the outside, with the latter being the major component of the outer leaflet and covering nearly three-quarters of the total outer cell surface. All LPSs possess the same general chemical architecture independently of bacterial activity (pathogenic, symbiotic, commensal), ecological niche (human, animal, soil, plant, water), or growth conditions. Endotoxins are large amphiphilic molecules consisting of a hydrophilic polysaccharide compo...
Formal Methods: Foundations and Applications
This book constitutes the refereed proceedings of the 23rd Brazilian Symposium on Formal Methods, SBMF 2020, which was supposed to take place in Ouro Preto, Brazil, in November 2020. Instead the symposium took place virtually due to the COVID-19 pandemic. The 10 regular papers presented together with 3 invited talks in this book were carefully reviewed and selected from 17 submissions. The papers are organized in topical sections such as: experience reports; models, languages and semantics; and software product lines. Chapter ‘Safety Assurance of a High Voltage Controller for an Industrial Robotic System’ is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
