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Pathway Analysis and Optimization in Metabolic Engineering
Facility in the targeted manipulation of the genetic and metabolic composition of organisms, combined with unprecedented computational power, is forging a niche for a new subspecialty of biotechnology called metabolic engineering. First published in 2002, this book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. The authors propose power-law models and methods of biochemical systems theory toward these ends. All concepts are derived from first principles, and the text is richly illustrated with numerous graphs and examples throughout. Special features include: nontechnical and technical introductions to models of biochemical systems; a review of basic methods of model design and analysis; concepts of optimization; and detailed case studies.
Peptaibiotics
Originally a special issue of Chemistry & Biodiversity, this is an excellent overview of the status of contemporary studies in peptaibiotics, covering aspects ranging from the search for novel bioactive compounds to considerations of their membrane-modifying properties.
The Metabolic Pathway Engineering Handbook, Two Volume Set
Christina Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer's yeast, is regarded as one of the most brilliant minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metab
Biotechnology and Biology of Trichoderma
Biotechnology and Biology of Trichoderma serves as a comprehensive reference on the chemistry and biochemistry of one of the most important microbial agents, Trichoderma, and its use in an increased number of industrial bioprocesses for the synthesis of many biochemicals such as pharmaceuticals and biofuels. This book provides individuals working in the field of Trichoderma, especially biochemical engineers, biochemists and biotechnologists, important information on how these valuable fungi can contribute to the production of a wide range of products of commercial and ecological interest. - Provides a detailed and comprehensive coverage of the chemistry, biochemistry and biotechnology of Trichoderma, fungi present in soil and plants - Includes most important current and potential applications of Trichoderma in bioengineering, bioprocess technology including bioenergy & biofuels, biopharmaceuticals, secondary metabolites and protein engineering - Includes the most recent research advancements made on Trichoderma applications in plant biotechnology and ecology and environment
Genomics of Plants and Fungi
This volume provides technical insight on how genomics-oriented studies may be used to bring new understanding to established models of fungal development. The book helps to assess and solve problems associated with multiple copies of genes and proteins with seemingly identical functions and depicts various industrial applications. To bridge the information gap resulting from this field's explosive growth, Genomics of Plants and Fungi addresses the implementation of workflow applications with the METEOR Workflow Management System, and discusses clinical manifestations of Aspergillus infection, stunted and medusa genes, hyphal mating and fertilization, and vegetative incompatibility.
Alcohol and its Role in the Evolution of Human Society
Archaelogists and anthropologists (especially ethnologists) have for many years realised that man's ingestion of alcoholic beverages may well have played a significant part in his transition from hunter-gatherer to agriculturalist. This unique book provides a scientific text on the subject of 'ethanol' that also aims to include material designed to show 'non-scientists' what fermentation is all about. Conversely, scientists may well be surprised to find the extent to which ethanol has played a part in evolution and civilisation of our species.
Industrial Applications
This volume gives a survey of the state of the art in the traditional fields of industrial mycology as well as of selected novel applications of fungi. The first section deals with the use of fungi in the production and processing of bread, cheese, beer and wine, traditional Asian fermentation products and edible mushrooms. The second section is devoted to the production of fungal metabolites and enzymes representing value-added products. In addition to antibiotics, alkaloids organic acids, vitamins and industrial enzymes, which have successfully been in use for decades, it is also dedicated to fungal metabolites, such as insecticidal and nematicidal compounds, immunosurppressants and flavor...
Agriculture and Food Production
Presenting a stimulating synthesis of rapidly growing research interests and publications by scholars in the field of applied mycology and biotechnology.The surge of research and development activity in applied mycology and fungal biotechnology relates to the need and utility of fungi in many contexts. These contexts are wide in scope, and include agriculture, animal and plant health, biotransformation of organic or inorganic matter, food safety, composition of nutrients and micronutrients, and human and animal infectious disease.Containing a balanced treatment of principles, biotechnological manipulations and applications of major groups of fungi in agriculture and food, this book will serve as a practical resource for mycologists, microbiologists, biotechnologists, bioengineers, scientists from agri-food industry, biochemists, botanists and agriculturists.
Plant Health Under Biotic Stress
The book illustrates the use of putative microbial agents which provide good protection to the plant from biotic pathogens attack. An up to date knowledge on plant-microbiome interaction strategies in terms of improved sustainability has been discussed. Information from experts across the globe on the application of microbes for providing amicable solution in sustainable agriculture has been gathered. In addition, information related to microbes mediated resistance levels leading to enhanced plant health has been well presented. The chapters have emphasised the use of Plant Growth Promoting Rhizobacteria (PGPR) and other potential biocontrol agents/antagonists in the management of plant diseases which provide extensive information to the readers. Literature on microbial root colonization, plant growth promotions, and also on the protection of plants from attack of various soil borne pathogens have been presented in a coherent way. Information on the application of potential strain of the bio-control fungi, endophytes, actinomycetes strengthening the plants ability which rescue the plant from pathogens attack leading to improved plant health has also been underpinned.
Novel Biotechnologies for Biocontrol Agent Enhancement and Management
The main scientists working with enhancing fungal, bacterial, virus and insect biological control agents on different targets present the latest progress in overcoming the barrier of insufficient virulence. This multi-disciplinary group review their own work and that of others, and describe the approaches being used, the successes and the barriers yet to be overcome. There is no up-to-date equivalent work describing biocontrol, let alone enhanced biocontrol.
