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Mutations in Human Genetic Disease
Different types of mutation can vary in size, from structural variants to single base-pair substitutions, but what they all have in common is that their nature, size and location are often determined either by specific characteristics of the local DNA sequence environment or by higher order features of the genomic architecture. The genomes of higher organisms are now known to contain "pervasive architectural flaws" in that certain DNA sequences are inherently mutation prone by virtue of their base composition, sequence repetitivity and/or epigenetic modification. In this volume, a number of different authors from diverse backgrounds describe how the nature, location and frequency of different types of mutation causing inherited disease are shaped in large part, and often in remarkably predictable ways, by the local DNA sequence environment.
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The End of Ethics and A Way Back
Bestselling author and professor Ted Malloch calls for real financial reform to restore confidence and fairness to a broken system From Ponzi schemes to the credit crisis to the real estate bubble, the financial industry seems to have lost its way on the road to riches. As private greed continues to undermine the public good, one might wonder what ever happened to business ethics. And how can we reform the global financial system to benefit everyone, rather than just the very lucky few? In The End of Ethics and the Way Back, the bestselling author of Doing Virtuous Business teams up with attorney and Yale University Postdoctoral Fellow, Jordan Mamorsky to examine the most recent failures of ...
Electron Paramagnetic Resonance in Biochemistry and Medicine
Electron Paramagnetic Resonance (EPR) spectroscopy - also sometimes termed Electron Spin Resonance spectroscopy - has manifold potential uses in biochemistry and medicine. The paramount importance of EPR spectroscopy applied to biological tissues and fluids is that it identifies the changes in redox processes that contribute to disease. EPR spectroscopy has come a long way from its original use to detect malignant tumors. For example, the development and later refinement of methods of low-temperature registration of biological tissues widened the scope of EPR spectroscopy. Innovations made possible by the introduction of spin labels, probes, and traps made EPR spectroscopy ever more applicab...
Handbook of Psychosocial Interventions for Veterans and Service Members
The Handbook of Psychosocial Interventions for Veterans and Service Members is a "one stop" handbook for non-military clinicians working with service members, veterans, and their families.
Natural Polymers, Biopolymers, Biomaterials, and Their Composites, Blends, and IPNs
Natural Polymers, Biopolymers, Biomaterials, and Their Composites, Blends, and IPNs focuses on the recent advances in natural polymers, biopolymers, biomaterials, and their composites, blends, and IPNs. Biobased polymer blends and composites occupy a unique position in the dynamic world of new biomaterials. The growing need for lubricious coatings and surfaces in medical devices—an outcome of the move from invasive to noninvasive medicines/procedures—is playing a major role in the advancement of biomaterials technology. Natural polymers have attained their cutting-edge technology through various platforms, yet there is a lot of novel information about them that is discussed in the book. This important work covers topics such as chitosan composites for biomedical applications and wastewater treatment, coal biotechnology, biomedical and related applications of second generation polyamidoamines, silk fibers, PEG hydrogels, bamboo fiber reinforced PE composites, jute/polyester composites, magnetic biofoams, and many other interesting aspects of importance to polymer research today.
Reviews in Fluorescence 2017
Reviews in Fluorescence 2017, the tenth volume of the book serial from Springer, serves as a comprehensive collection of current trends and emerging hot topics in the field of fluorescence and closely related disciplines, such as fluorescence based plasmonics. It summarizes the year’s progress in fluorescence and its applications, with authoritative reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of fluorescence. Reviews in Fluorescence offers an essential reference material for any research lab or company working in the fluorescence field and related areas. All academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in the continuously emerging field of fluorescence will find it an invaluable resource.
