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A sociedade tem lidado com diversas mudanças que decorrem do advento e da expansão das tecnologias digitais. No bojo do que podemos chamar de cultura digital, os processos educacionais também são compelidos à ressignificação, demandando olhares críticos daqueles que pensam e fazem a educação. Esta obra, portanto, reúne contribuições de diferentes pesquisadores e pesquisadoras que, com o olhar atento às instituições e processos, da educação básica ao ensino superior, se debruçam sobre os desafios da didática e da formação docente na cultura digital.
The current world biodiversity consists of an inestimable amount of living forms, that at all levels, from genes to biomes, from individuals to populations, from species to communities, are in constant pursuit of the best strategies to react to the natural and anthropic environmental changes. The arrangement of new and dynamic ecosystems balanced by the formation and the vanishing of species, is the direct consequence of these changes. This book contains comprehensive overviews and original studies focused on ecological and ecosystem functioning studies, hazards and conservation management, assessment of environmental variables affecting species diversity, also considering species richness and distribution, in order to identify the best management strategies to face and solve the conservation problems.
This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.
In recent years, powered by evolving technologies and experimental design, studies have better illuminated the regulating role of proteolytic enzymes across human development and pathologies. Proteolytic Signaling in Health and Disease provides an in-depth discussion of fundamental physiological and developmental processes regulated by proteases, from protein turnover and autophagy to antigen processing and presentation and major histocompatibility complex (MHC) molecules. Moving on from basic biology, international chapter authors examine a range of pathological conditions associated with proteolysis, including inflammation, wound healing, and cancer. Later chapters discuss the newly discov...
In 2022, the Landscape Architecture course in Portugal celebrated 80 years of existence. This edited collection, Portuguese Landscape Architecture Education, Heritage and Research, commemorates this important milestone by bringing together some of the most respected names in Portuguese Landscape Architecture. Although the book’s content is targeted at the assessment of the Portuguese history and influence, the themes under analysis are all-encompassing within the major fields, namely pedagogy; heritage; theory and methods; and design and landscape planning and management. The book seeks to address several research questions, including How has Landscape Architecture evolved in Portugal and ...
Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores
Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation, characterization, applications, regulations and the latest advances. Sections introduce the fundamental aspects of PLGA nanoparticles for drug delivery, including properties, preparation methods, characterization, drug loading methods, and drug release mechanisms, along with a focus on applications. Application of PLGA nanoparticles for the treatment of cancer, inflammatory, cerebral, cardiovascular, and infectious diseases, as well as in regenerative medicine, photodynamic and photothermal therapy, and gene therap...
This clinical casebook is comprised of surgical cases involving the most important cardiovascular diseases in a concise, easy-to-read format (5x8 in trim size, like other titles in this burgeoning, informal product line in the Springer clinical medicine program). Each chapter is a case that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as questions and answers (between 8 and 10) about relevant aspects related to the diagnosis and treatment of the addressed disease. The Q&A section will broaden discussion and increase the title's pedagogical value. The casebook features 40 surgical cases in...
The book addresses contemporary challenges related to chronicity in the context of life and health. The book is structured across 11 core axes to aid healthcare professionals in understanding the topic. The axes address issues such as health promotion and quality of life, the transition from ephemerality to chronicity throughout life, the presence of chronicity in childhood and adolescence, violence against transgender people, the coexistence of communicable and non-communicable chronic diseases in the community, work-related chronic diseases, chronicity in the elderly, and strategies for sustainable development in this context. It discusses the importance of palliative care for patients facing finitude and explores the role of spirituality in coping with chronicity. In summary, the book aims to present a comprehensive and multidimensional perspective on chronicity, providing valuable insights for the teaching, research, extension, and care sectors.