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Virus Discovery by Metagenomics: The (Im)possibilities
Since the late 1800s, the discovery of new viruses was a gradual process. Viruses were described one by one using a suite of techniques such as (electron) microscopy and viral culture. Investigators were usually interested in a disease state within an organism, and expeditions in viral ecology were rare. The advent of metagenomics using high-throughput sequencing has revolutionized not only the rate of virus discovery, but also the nature of the discoveries. For example, the viral ecology and etiology of many human diseases are being characterized, non-pathogenic viral commensals are ubiquitous, and the description of environmental viromes is making progress. This Frontiers in Virology Research Topic showcases how metagenomic and bioinformatic approaches have been combined to discover, classify and characterize novel viruses.
American Trinity
American Trinity is for everyone who loves the American West and wants to learn more about the good, the bad, and the ugly. It is a sprawling story with a scholarly approach in method but accessible in manner. In this innovative examination, Dr. Larry Len Peterson explores the origins, development, and consequences of hatred and racism from the time modern humans left Africa 100,000 years ago to the forced placement of Indian children on off-reservation schools far from home in the late 1800s. Along the way, dozens of notable individuals and cultures are profiled. Many historical events turned on the lives of legendary Americans like the "Father of the West," Thomas Jefferson, and the "Son o...
The Night Hawks
There's nothing Ruth Galloway hates more than amateur archaeologists, but when a group of them stumble upon Bronze Age artifacts alongside a dead body, she finds herself thrust into their midst--and into the crosshairs of a string of murders circling ever closer.
Disease Dispersion and Impact in the Indian Ocean World
This volume views the study of disease as essential to understanding the key historical developments underpinning the foundation of contemporary Indian Ocean World (IOW) societies. The interplay between disease and climatic conditions, natural and manmade crises and disasters, human migration and trade in the IOW reveals a wide range of perceptions about disease etiologies and epidemiologies, and debates over the origin, dispersion and impact of disease form a central focus in these essays. Incorporating a wide scope of academic and scientific angles including history, social and medical anthropology, archaeology, epidemiology and paleopathology, this collection focuses on diseases that spread across time, space and cultures. It scrutinizes disease as an object, and engages with the subjectivities of afflicted inhabitants of, and travellers to, the IOW.
The Stockholm Paradigm
The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a...
Palaeolithic Europe
In this book, Jennifer French presents a new synthesis of the archaeological, palaeoanthropological, and palaeogenetic records of the European Palaeolithic, adopting a unique demographic perspective on these first two-million years of European prehistory. Unlike prevailing narratives of demographic stasis, she emphasises the dynamism of Palaeolithic populations of both our evolutionary ancestors and members of our own species across four demographic stages, within a context of substantial Pleistocene climatic changes. Integrating evolutionary theory with a socially oriented approach to the Palaeolithic, French bridges biological and cultural factors, with a focus on women and children as the drivers of population change. She shows how, within the physiological constraints on fertility and mortality, social relationships provide the key to enduring demographic success. Through its demographic focus, French combines a 'big picture' perspective on human evolution with careful analysis of the day-to-day realities of European Palaeolithic hunter-gatherer communities—their families, their children, and their lives.
Never Too Late
"Within the pages of this book, readers learn how to confidently take charge of their sexual health and protect themselves and their partners against sexually transmitted diseases"--
