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Gamma Knife Neurosurgery in the Management of Intracranial Disorders II
The articles in this volume cover the various radiosurgical techniques used to treat benign and malignant intracranial tumors, cavernous malformations, and functional disorders, as well as a wide array of specific details on medical physics, neuroimaging, and anesthetic support. Particular emphasis is put on the optimal combination of microneurosurgery and radiosurgery for attaining the best functional results in patients with vestibular schwannomas, craniopharyngiomas, and pituitary adenomas, and on the most effective methods of treatment planning and radiation dosimetry in cases of metastatic brain tumors. The highlighted clinical aspects include indications for radiosurgery and the predic...
Advances in the Biology, Imaging and Therapies for Glioblastoma
This book is intended for physicians and scientists with interest in glioblastoma biology, imaging and therapy. Select topics in DNA repair are presented here to demonstrate novel paradigms as they relate to therapeutic strategies. The book should serve as a supplementary text in courses and seminars as well as a general reference.
CNS Cancer
Cancers of the central nervous system are among the most lethal of human neoplasms. They are recalcitrant to even intensive multimodality therapies that include surgery, radiotherapy, and chemotherapy. Moreover, especially in children, the consequences of these therapies can itself be devastating and involve serious cognitive and developmental disorders. It is small wonder that such cancers have come under the intense scrutiny of each of the subspecialties of clinical care and investigation as well as attracting some of the best basic research scientists. Their joint efforts are gradually peeling away the mysteries surrounding the genesis and progression of these tumors and inroads are being...
Frontiers in Anti-Cancer Drug Discovery
Frontiers in Anti-Cancer Drug Discovery is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The Ebook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The Ebook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.
Oncogenomics and Cancer Proteomics
Oncogenomics and Cancer Proteomics - Novel Approaches in Biomarkers Discovery and Therapeutic Targets in Cancer presents comprehensive reviews of the most common cancers from bench to bedside applications by an international team of experts. This book will contribute to the scientific and medical community by providing up-to-date discoveries of oncogenomics and their potential applications in cancer translational research. It is intended for students, scientists, clinicians, oncologists and health professionals working in cancer research.
Selected Topics in DNA Repair
This book is intended for students and scientists working in the field of DNA repair, focusing on a number of topics ranging from DNA damaging agents and mechanistic insights to methods in DNA repair and insights into therapeutic strategies. These topics demonstrate how scientific ideas are developed, tested, dialogued, and matured as it is meant to discuss key concepts in DNA repair. The book should serve as a supplementary text in courses and seminars as well as a general reference for biologists with an interest in DNA repair.
Intracranial Gliomas Part III - Innovative Treatment Modalities
At present most intracranial gliomas are considered incurable with current treatment strategies, and the search for new modalities that may effectively control tumor growth continues. The chapters in this volume describe basic principles and therapeutic possibilities of several innovative techniques, including photodynamic therapy, laser-induced interstitial thermotherapy, stereotactic cryodestruction, high-intensity focused ultrasound ablation, boron neutron capture therapy, proton and carbon ion irradiation, targeted therapy, immunotherapy, gene therapy, local chemotherapy, and alternating electric fields therapy. Potential applications of extracellular vesicles and nanotechnology for management of gliomas are highlighted as well. Many of these methods have already demonstrated antitumor efficacy in clinical testing, whereas others are still under development. The materials presented in this book are mainly directed at clinicians treating patients with brain tumors, as well as clinical and basic researchers working in the field of neuro-oncology.
Intrinsic and Skull Base Tumors - E-Book
Unique in the field, Intrinsic and Skull Base Tumors presents commonly encountered skull base and intrinsic neoplasm cases with side-by-side, case-by-case comparisons that clearly show how various experts would handle the same case. This inaugural volume in the Neurosurgery: Case Comparison Series offers multiple opinions from international experts in neurosurgery who provide various approaches and management styles for the same case. This format allows for quick and helpful comparisons of different ways to approach a lesion, advantages and disadvantages of each approach, and what each expert is looking for in how they would manage a particular case. Offers 3 to 4 expert opinions on each cas...
Chiral Reagents for Asymmetric Synthesis
Derived from the renowned, Encyclopedia of Reagents for Organic Synthesis (EROS), the related editors have created a new handbook which focuses on chiral reagents used in asymmetric synthesis and is designed for the chemist at the bench. This new handbook follows the same format as the Encyclopedia, including an introduction and an alphabetical arrangement of the reagents. As chiral reagents are the key for the successful asymmetric synthesis, choosing the right reagents is essential, in this handy reference the editors give details on how to prepare, store and use the reagents as well as providing key reactions to demonstrate where reagents have been successfully used. Comprehensive information on 226 reagents Covers 64 reagents which were not included in EROS All information in one easy to use volume – at an affordable price All reagents included will be added to e-EROS – please visit the site where you can gain access to over 50,000 reactions and 3,800 of the most frequently consulted reagents. Visit: www.interscience.wiley.com/eros
