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Molecular Aspects of Aging
Molecular Aspects of Aging: Understanding Lung Aging covers recent research in the mechanisms that contribute to cellular senescence. Covering universal themes in aging, such as the exhaustion of stem cells and subsequent loss of the regenerative refueling of organs as well as immunosenescence, this text illuminates new directions for research not yet explored in the still poorly investigated area of molecular mechanisms of lung aging. The molecular nature of general aging processes is explored with targeted coverage on how to analyze lung aging through experimental approaches.
The Elasticity of Life
Elasticity is absolutely necessary for living a normal life. This fact is cruelly revealed when respiratory, cardiac, digestive, sensory, motor, reproductive or aesthetic problems appear following the inexorable decline of our elastic capital. The protection and maintenance of this capital is one of life’s priorities since this declination begins at the age of twenty and accelerates in times of crises and pandemics. However, there are no therapies yet designed to remedy it. The first part of the book explains the consequences surrounding a lack of elasticity in the skin, the most visible decline, and then other defects in elasticity throughout our bodies, exploring places rarely mentioned. The second part describes the research fighting against elasticity anomalies and examines useful behaviors to protect our elastic capital (e.g. our diets and physical and cognitive activities). This last point is at the heart of current social debates on nutritional, behavioral, environmental and even ethical levels.
The Aging Lungs
"This volume provides a comprehensive and multi-disciplinary overview of the aging lung, written by the main researchers in the field. Current physiological, cellular and molecular understanding of how the lungs age and the relationship to age-associated lung diseases will be presented. The contents are aimed at a broad audience of scientists and clinicians with an interest in the respiratory system, pathogenesis of age-associated lung diseases and clinical implications."--
Progress in Nucleic Acid Research and Molecular Biology
Progress in Nucleic Acid Research and Molecular Biology provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references.
Aging Lungs, The: Mechanisms And Clinical Sequelae
This volume provides a comprehensive and multi-disciplinary overview of the aging lung, written by the main researchers in the field. Current physiological, cellular and molecular understanding of how the lungs age and the relationship to age-associated lung diseases will be presented. The contents are aimed at a broad audience of scientists and clinicians with an interest in the respiratory system, pathogenesis of age-associated lung diseases and clinical implications.
L’élasticité du vivant
L’élasticité est absolument nécessaire pour vivre une vie normale. Ce fait se révèle cruellement lorsque des problèmes physiques, respiratoires, cardiaques, digestifs, sensoriels, moteurs, reproductifs ou esthétiques apparaissent à la suite de l’inexorable déclin de notre capital élastique. Cette déclinaison commence à la fin de la croissance et s’accélère en temps de crise (et de pandémie). La protection et l’entretien de ce capital est donc une des priorités de la vie. Cependant, il n’existe pas encore de thérapie conçue pour y remédier. L’élasticité du vivant définit tout d’abord les conséquences dérivant d’un manque d’élasticité de la peau – le déclin le plus visible, puis d’autres défauts d’élasticité dans notre corps, souvent insoupçonnés et rarement mentionnés. Cet ouvrage présente ensuite les recherches luttant contre les anomalies d’élasticité et examine les comportements utiles pour protéger notre capital élastique (alimentation, activités physiques et cognitives, etc.). Ce dernier point est au coeur des débats de société actuels sur les plans nutritionnel, comportemental, environnemental, voir éthique.
Innovative 3D models for Understanding Mechanisms underlying Lung Diseases: Powerful Tools for Translational Research
The mechanisms underlying acute and chronic lung diseases are complex, reflecting the interplay between multiple cell types, their microenvironment and exogenous challenges. While traditional in vitro cell culture approaches have been instrumental in advancing our knowledge of cellular signalling and function, they typically lack the cell-cell and cell-matrix interactions that define the niche in which lung cell and tissue functions emerge. Implementing in vivo and ex vivo three-dimensional (3D) models more realistically mimicking the in vivo cell-extracellular matrix (ECM) crosstalk should facilitate a considerable leap towards better understanding lung diseases and thus in investigating ne...
