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Not only does this book provide a comprehensive review of current research advances in collagen structure and mechanics, it also explores this biological macromolecule’s many applications in biomaterials and tissue engineering. Readers gain an understanding of the structure and mechanical behavior of type I collagen and collagen-based tissues in vertebrates across all length scales, from the molecular (nano) to the organ (macro) level.
This book aims at providing insights into the collagen superfamily and the remarkable diversity of collagen function within the extracellular matrix. Additionally, the mechanisms underlying collagen-related diseases such as dystrophic epidermolysis bullosa, osteogenesis imperfecta, as well as collagen-related myopathies and neurological disorders are discussed. Collagens are the most abundant extracellular matrix proteins in organisms. Their primary function is to provide structural support and strength to cells and to maintain biomechanical integrity of tissues. However, collagens can no longer be considered just as structural proteins. They can act as extracellular modulators of signaling ...
This detailed volume compiles state-of-the-art protocols that will serve as recipes for scientists researching collagen, an abundant protein with great importance to health and disease, as well as in applications like food, cosmetics, pharmaceuticals, cosmetic surgery, artificial skin, and glue. Beginning with a section on in vitro models for the characterization of collagen formation, the book continues by highlighting large-scale analysis of collagen with mass spectrometry in order to elucidate the proteomics, degradomics, interactomes, and cross-linking of collagen, high resolution imaging approaches for collagen by the use of scanning electron microscopy and multiphoton imaging, as well ...
Structure and Function of Collagen Types is a collection of articles that reviews the different types of collagens (Type I to XI). Each article focuses on a particular type of collagen and written by leading investigators in the collagen field. The book begins with a review of the fibril forming collagens (types I, II, and III) and traces the early work on the structure of these collagens to our knowledge of the structure of the collagen genes. This chapter is followed by a detailed description of type IV (basement membrane) collagen. Chapter 3 addresses the biosynthesis and chain assembly of type V collagen. The evidence that type VI collagen is assembled to form tetramers is presented in c...
Jessica Bippen, registered dietitian and founder of the popular Nourished by Nutrition blog, offers a captivating introduction to dietary collagen supplements and how to use them for personal wellness. Gorgeously packaged, it’s perfect for the GOOP and Well+Good audience, for yourself, or as a gift. Dietary collagen offers a unique blend of amino acids and other compounds that are essential for maintaining the structure and integrity of almost every part of the body and at every age. It can improve the health of our skin, hair, nails, bones, and joints, as well as our digestive and immune systems. Registered dietitian Jessica Bippen shares her knowledge of this protein and explains why the...
An authoritative, illustrated, and easy-to-follow guide to collagen and how it can enhance your health—from rejuvenating hair and skin to treating bones and joints. Collagen, in the form of supplements and additives, and in natural sources, has become one of today’s most popular paths to wellness. But what exactly is collagen, how is it produced, and how can you incorporate it into your diet? The Collagen Handbook is an essential resource for understanding the benefits of collagen in your diet and learning how to incorporate the fountain of youth into your everyday wellness routine. Featuring 40 recipes, this book will help those looking to rejuvenate their skin, improve gut health, ease arthritis symptoms, or simply ward off degeneration in muscles and tissues in the body. Topics that are discussed include the difference between collagen and gelatin, various sources of collagen and supplements, and the status of collagen and FDA testing.
From the bestselling author of Keto Diet "An essential read. The Collagen Diet tells us why collagen is important, why it is so lacking diet in our modern diet, and, most important, what we can do to bring collagen back in the fold in terms of being an amazing protein that we should all be getting more of."-David Perlmutter, MD, author of Grain Brain and the forthcoming Brain Wash "Collagen shows up in nearly every part of the body, from your hair and skin to your arterial walls, gastrointestinal tract, and even your eyes. Dr. Axe presents the science behind this miraculous substance, and explains how you can use it to fight chronic pain, digestive issues, skin issues, and so much more."--Dr...
This book describes every manner in which collagen is involved in normal anddisease-altered states of the various organs and systems. In the first part of the book the biochemical aspects of collagens are reviewed, including their structure, heterogeneity, syntheses, and degradation. The main part focuses on the involvement of collagen in bone, cartilage, tendon, muscle, heart, vessels, lungs, liver, skin, eye, ear, teeth, periodontal tissues, kidneys and reproductive, hemopoietic,and nervous systems. The influence of radiation and nutrition on collagen, the role of collagen in neoplasms, the hormonal control of its metabolism, immunobiology and the pharmacology of collagen are also describe...
J. Brinckmann: Collagens at a Glance.- J. Engel, H.P. Bächinger: Structure, Stability and Folding of the Collagen Triple Helix.- S. Ricard-Blum, F. Ruggiero, M. van der Rest: The Collagen Superfamily.- T. Koide, K. Nagata: Collagen Biosynthesis.- J. Myllyharju: Intracellular Post-Translational Modifications of Collagens.- D.S. Greenspan: Biosynthetic Processing of Collagen Molecules.- D.E. Birk, P. Bruckner: Collagen Suprastructures.- D.R. Eyre, J.-J. Wu: Collagen Cross-Links