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Toward Precision Medicine
Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerge...
Towards Holistic Medicine
Holistic medicine is: A clinical discipline that integrates both Eastern and Western medical methods and knowledge systems into one An evidence-based medicine that simultaneously embodies both a holistic approach and personalized principles The most straightforward form of medicine that adheres to scientific standards and effectively meets the needs of humanity In recent years, the integrated research on living organisms initiated by systems biology, along with the efforts of precision medicine to tailor treatment plans based on the individual characteristics of each patient, have opened up the process of modern biology and medicine returning to the ideas of Chinese medical traditions. Under...
The New ABCs of Research
This book is a guide for junior researchers, and a manifesto for senior researchers and policy makers about how to update policies to respond to the immense challenges of our times. The guiding principles are to combine applied and basic research in ways that use the methods of science, engineering, and design.
The RASopathies
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Advancing Healthcare Through Personalized Medicine
This book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it helps to mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to the underlying concepts at the heart of personalized medicine. An innovative second edition, this book functions as an update to the successful first edition to include new, state-of-the-art information and advancements in the fast-paced field of personalized medicine. Chapters examine pharmacogenomics, targeted therapies, individualized diagnosis and treatment, and cancer immunotherapies. The book also features an essential discussion on how the advent of genomic techn...
Osteoarthritis
This comprehensive book grants readers exclusive insight into current advancements in the field of osteoarthritis (OA). Contributions from leading scientists and clinicians provide a detailed introduction into current understanding of the pathogenesis of OA, different joint structures affected by this debilitating disease (hip, knee, elbow, shoulder, foot, ankle, hand, wrist, and spine), current knowledge and practice in imaging, joint conservative strategies, OA biomarkers as well as currently available treatments, their safety profile and future therapeutic targets. This book further discusses the potential of regenerative therapies and recent advances in OA Personalized Medicine, and how collection of OA patient’s phenotypic, genetic and proteomic data is able to direct treatment strategies through Bio-Informatics.
Bioscience - Lost in Translation?
Examines the global issue of biomedical research increasingly failing to deliver patient benefits and health system improvement. The book highlights the problem and its consequences, and analyses the underlying causative factors and provides powerful prescriptions for change to close the 'innovation gap'.
Artificial Intelligence and Computational Dynamics for Biomedical Research
This work presents the latest development in the field of computational intelligence to advance Big Data and Cloud Computing concerning applications in medical diagnosis. As forum for academia and professionals it covers state-of-the-art research challenges and issues in the digital information & knowledge management and the concerns along with the solutions adopted in these fields.
Charney & Nestler's Neurobiology of Mental Illness
In the years following publication of the DSM-5(R), the field of psychiatry has seen vigorous debate between the DSM's more traditional, diagnosis-oriented approach and the NIMH's more biological, dimension-based RDoC (research domain criteria) approach. Charney & Nestler's Neurobiology of Mental Illness is an authoritative foundation for translating information from the laboratory to clinical treatment, and its fifth edition extends beyond this reference function to acknowledge and examine the controversies, different camps, and thoughts on the future of psychiatric diagnosis. In this wider context, this book provides information from numerous levels of analysis, including molecular biology...
Convergence of Knowledge, Technology and Society
This volume aims to document the most important worldwide accomplishments in converging knowledge and technology, including converging platforms, methods of convergence, societal implications, and governance in the last ten years. Convergence in knowledge, technology, and society is the accelerating, transformative interaction among seemingly distinct scientific disciplines, technologies, and communities to achieve mutual compatibility, synergism, and integration, and through this process to create added value for societal benefit. It is a movement that is recognized by scientists and thought leaders around the world as having the potential to provide far-reaching solutions to many of todayâ...
