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La escritora Rosa María Ramírez Moya viene de una familia campesina originaria de Guateque, Boyacá, Colombia; ella es la cuarta de siete hermanos y se siente orgullosa de haber nacido en la bella región del Valle de Tenza. Este es el momento para explicar la singularidad de Rosa María, poetisa, cuentista, ensayista, de inspiración objetiva, directa y escritora de varias obras. Lo primero que destaca en sus escritos ya sean poéticos o en prosa es el terreno elegido para desplegar las herramientas de su oficio "el amor a la Naturaleza". Lo segundo es el tono y el reconocimiento que hace a los seres o lugares que son dignos de elogios, características animadoras de su trabajo; el apreci...
Magnetic Resonance Imaging (MRI) is a unique technique that provides tissue-specific contrast non-invasively. However, even at ultra-high field, resolution remains on the millimeter scale, far above cellular microstructure. Taking the fact that diffusion of nuclear spins in magnetic field gradients results in a characteristic signal loss, MRI can be sensitized to water-diffusion (DW-MRI) to recover microstructural information indirectly. Diffusion-Weighted MR Spectroscopy (DW-MRS) goes one step further by not measuring the diffusion of tissue water but of cell-type specific metabolites. Given that, both techniques can provide complementary information: DW-MRI on water diffusion with high spa...
Multiple Sclerosis (MS) is a chronic neurodegenerative disease which is mainly characterized by inflammation, demyelination, and axonal loss. Conventional Magnetic Resonance Imaging (MRI) has become the most established imaging tool in the diagnosis and follow-up of MS in clinical practice. However, the high sensitivity of these standard MRI techniques is mainly restricted to the detection of focal demyelinating MS lesions, mainly in white matter (WM), as they fail to depict further damage in normal appearing WM (NAWM) and grey matter (GM) involvement. More advanced quantitative MRI methods, including diffusion MRI, have been applied in MS research and they have improved the detection and in...
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